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    AMY2A amylase, alpha 2A (pancreatic) [ Pan troglodytes (chimpanzee) ]

    Gene ID: 736558, updated on 3-Dec-2024

    Summary

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    Gene symbol
    AMY2A
    Gene description
    amylase, alpha 2A (pancreatic)
    Locus tag
    CK820_G0020822
    See related
    Ensembl:ENSPTRG00000049749
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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    Genomic context

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    See AMY2A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (127540900..127556298, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (103742997..103758384)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene AP-2 complex subunit beta-like Neighboring gene amylase alpha 1C Neighboring gene actin, cytoplasmic 2-like Neighboring gene amylase alpha 2B Neighboring gene RNA binding region (RNP1, RRM) containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diet and the evolution of human amylase gene copy number variation. Perry GH, et al. Nat Genet, 2007 Oct. PMID 17828263, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-amylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cation binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pancreatic alpha-amylase
    Names
    alpha-amylase
    NP_001103628.1
    XP_009424904.4
    XP_009424911.4
    XP_016785386.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110158.1 → NP_001103628.1  pancreatic alpha-amylase precursor

      See identical proteins and their annotated locations for NP_001103628.1

      Status: PROVISIONAL

      Source sequence(s)
      EU022323
      UniProtKB/TrEMBL
      A0A2J8MHT1, A8HDG8
      Conserved Domains (3) summary
      cd11317
      Location:25 → 416
      AmyAc_bac_euk_AmyA; Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase)
      smart00632
      Location:423 → 510
      Aamy_C; Aamy_C domain
      COG0366
      Location:46 → 315
      AmyA; Glycosidase [Carbohydrate transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      127540900..127556298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009426629.5 → XP_009424904.4  pancreatic alpha-amylase isoform X1

      UniProtKB/TrEMBL
      A0A2J8MHT1, H2PZI5

    2. XM_016929897.4 → XP_016785386.3  pancreatic alpha-amylase isoform X1

      UniProtKB/TrEMBL
      A0A2J8MHT1, H2PZI5

    3. XM_009426636.4 → XP_009424911.4  pancreatic alpha-amylase isoform X2

      UniProtKB/TrEMBL
      A0A2J8MHT1
    Nucleotide Protein
    Heading Accession and Version

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