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    THAPSDRAFT_31845 lipoic acid synthetase [ Thalassiosira pseudonana CCMP1335 ]

    Gene ID: 7452159, updated on 21-Dec-2023

    Summary

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    Gene symbol
    THAPSDRAFT_31845
    Gene description
    lipoic acid synthetase
    Locus tag
    THAPSDRAFT_31845
    Gene type
    protein coding
    RNA name
    lipoic acid synthetase
    RefSeq status
    PROVISIONAL
    Organism
    Thalassiosira pseudonana CCMP1335 (strain: CCMP1335)
    Lineage
    Eukaryota; Stramenopiles; Bacillariophyta; Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; Thalassiosira
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    Genomic context

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    See THAPSDRAFT_31845 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_012065.1 (113697..114854, complement)

    Chromosome 2 - NC_012065.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_012065.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism. Armbrust EV, et al. Science, 2004 Oct 1. PMID 15459382
    2. The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Bowler C, et al. Nature, 2008 Nov 13. PMID 18923393
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipoate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipoate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Names
    lipoic acid synthetase
    XP_002287622.1
    • Putative lipoic acid synthetase (lipoate synthase), similar to gi|23821835|sp|Q99M04|LIAS_MOUSE Lipoic acid synthetase, mitochondrial precursor (Lip-syn) (Lipoate synthase) (mLIP1) (model%: 100, hit%: 78, score: 955, %id: 61) [Mus musculus]

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_012065.1 Reference assembly

      Range
      113697..114854 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002287586.1 → XP_002287622.1  lipoic acid synthetase, partial [Thalassiosira pseudonana CCMP1335]

      See identical proteins and their annotated locations for XP_002287622.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      B8BTB6
      Conserved Domains (3) summary
      cd01335
      Location:130 → 328
      Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
      PLN02428
      Location:1 → 373
      PLN02428; lipoic acid synthase
      pfam16881
      Location:3 → 96
      LIAS_N; N-terminal domain of lipoyl synthase of Radical_SAM family
    Nucleotide Protein
    Heading Accession and Version

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