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    Prr3 proline-rich polypeptide 3 [ Mus musculus (house mouse) ]

    Gene ID: 75210, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Prr3provided by MGI
    Official Full Name
    proline-rich polypeptide 3provided by MGI
    Primary source
    MGI:MGI:1922460
    See related
    Ensembl:ENSMUSG00000038500 AllianceGenome:MGI:1922460
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cat56; 4930540G07Rik
    Summary
    Predicted to enable metal ion binding activity. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human PRR3 (proline rich 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 13.4), whole brain E14.5 (RPKM 13.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Prr3 in Genome Data Viewer
    Location:
    17 B1; 17 18.81 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36283431..36291136, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35972539..35980244, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1, regulatory subunit 10 pseudogene Neighboring gene ATP-binding cassette, sub-family F member 1 Neighboring gene microRNA 877 Neighboring gene STARR-positive B cell enhancer ABC_E8674 Neighboring gene predicted gene, 32655 Neighboring gene guanine nucleotide binding protein-like 1 Neighboring gene RIKEN cDNA A930015D03 gene Neighboring gene STARR-positive B cell enhancer ABC_E5609 Neighboring gene STARR-positive B cell enhancer ABC_E8921 Neighboring gene STARR-positive B cell enhancer ABC_E959 Neighboring gene STARR-positive B cell enhancer ABC_E4214 Neighboring gene STARR-positive B cell enhancer ABC_E5610 Neighboring gene STARR-positive B cell enhancer ABC_E9951 Neighboring gene histocompatibility 2, T region locus 24 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:36157683-36157870 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:36160698-36160881 Neighboring gene STARR-positive B cell enhancer ABC_E8675 Neighboring gene histocompatibility 2, T region locus 23

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
    2. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    3. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    4. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 3
    Names
    MHC class I region proline-rich protein Cat56

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001165892.2 → NP_001159364.1  proline-rich protein 3 isoform b

      See identical proteins and their annotated locations for NP_001159364.1

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Consensus CDS
      CCDS50099.1
      UniProtKB/TrEMBL
      E9Q601, G3UZI1
      Related
      ENSMUSP00000125802.3, ENSMUST00000165613.9

    2. NM_001282012.2 → NP_001268941.1  proline-rich protein 3 isoform c

      See identical proteins and their annotated locations for NP_001268941.1

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Consensus CDS
      CCDS70807.1
      UniProtKB/TrEMBL
      Q3V0R7, Q4W8V0
      Related
      ENSMUSP00000129651.2, ENSMUST00000172429.8
      Conserved Domains (1) summary
      pfam00642
      Location:112 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    3. NM_001282013.2 → NP_001268942.1  proline-rich protein 3 isoform c

      See identical proteins and their annotated locations for NP_001268942.1

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Consensus CDS
      CCDS70807.1
      UniProtKB/TrEMBL
      Q3V0R7, Q4W8V0
      Conserved Domains (1) summary
      pfam00642
      Location:112 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    4. NM_001282024.2 → NP_001268953.1  proline-rich protein 3 isoform c

      See identical proteins and their annotated locations for NP_001268953.1

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Consensus CDS
      CCDS70807.1
      UniProtKB/TrEMBL
      Q3V0R7, Q4W8V0
      Conserved Domains (1) summary
      pfam00642
      Location:112 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    5. NM_001282025.2 → NP_001268954.2  proline-rich protein 3 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC112970
      UniProtKB/TrEMBL
      E9Q601, G3UZI1
      Related
      ENSMUSP00000134115.2, ENSMUST00000172900.8

    6. NM_001384114.1 → NP_001371043.1  proline-rich protein 3 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC112970
      UniProtKB/Swiss-Prot
      Q811B5, Q91YI5
      Conserved Domains (1) summary
      pfam00642
      Location:159 → 183
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    7. NM_001384116.1 → NP_001371045.1  proline-rich protein 3 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Conserved Domains (1) summary
      pfam00642
      Location:62 → 86
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    8. NM_001384117.1 → NP_001371046.1  proline-rich protein 3 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Conserved Domains (1) summary
      pfam00642
      Location:55 → 79
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    9. NM_145487.4 → NP_663462.2  proline-rich protein 3 isoform a

      See identical proteins and their annotated locations for NP_663462.2

      Status: VALIDATED

      Source sequence(s)
      AC112970
      Consensus CDS
      CCDS28714.1
      UniProtKB/Swiss-Prot
      Q811B5, Q91YI5
      Related
      ENSMUSP00000052166.8, ENSMUST00000055454.14
      Conserved Domains (1) summary
      pfam00642
      Location:159 → 183
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      36283431..36291136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030250122.2 → XP_030105982.1  proline-rich protein 3 isoform X1

    2. XM_036160820.1 → XP_036016713.1  proline-rich protein 3 isoform X2

    RNA

    1. XR_001782124.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q811B5.1 GenPept UniProtKB/Swiss-Prot:Q811B5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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