U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    RRP45a ribonuclease PH45A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820485, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    RRP45a
    Official Full Name
    ribonuclease PH45A
    Primary source
    TAIR:AT3G12990
    Locus tag
    AT3G12990
    See related
    Araport:AT3G12990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MGH6.11; ribonuclease PH45A
    Summary
    Encodes a 3'-5' exoribonucleasely redundant with CER7. Involved in epicuticular wax biosynthesis.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See RRP45a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (4156054..4158004)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene histone acetyltransferase of the CBP family 5 Neighboring gene miscRNA Neighboring gene ubiquinone biosynthesis protein (Protein of unknown function, DUF547) Neighboring gene hAT transposon superfamily protein Neighboring gene hAT transposon superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A core subunit of the RNA-processing/degrading exosome specifically influences cuticular wax biosynthesis in Arabidopsis. Hooker TS, et al. Plant Cell, 2007 Mar. PMID 17351114, Free PMC Article
    2. The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana. Lange H, et al. PLoS Genet, 2014 Aug. PMID 25144737, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001202945.2
    NM_001338017.1
    NM_001338018.1
    NM_112136.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables 3'-5'-RNA exonuclease activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within wax biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    part_of exosome (RNase complex) IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ribonuclease PH45A
    NP_001189874.1
    • ribonuclease PH45A (RRP45a); CONTAINS InterPro DOMAIN/s: Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: 3'-5'-exoribonuclease family protein (TAIR:AT3G60500.3).
    NP_001319535.1
    • ribonuclease PH45A (RRP45a); CONTAINS InterPro DOMAIN/s: Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: 3'-5'-exoribonuclease family protein (TAIR:AT3G60500.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_566441.1
    • ribonuclease PH45A (RRP45a); CONTAINS InterPro DOMAIN/s: Exoribonuclease, phosphorolytic domain 2 (InterPro:IPR015847), Exoribonuclease, phosphorolytic domain 1 (InterPro:IPR001247), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: 3'-5'-exoribonuclease family protein (TAIR:AT3G60500.3); Has 1192 Blast hits to 1192 proteins in 317 species: Archae - 241; Bacteria - 12; Metazoa - 352; Fungi - 188; Plants - 158; Viruses - 0; Other Eukaryotes - 241 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4156054..4158004
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202945.2 → NP_001189874.1  ribonuclease PH45A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189874.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LGD7, Q9LDM2
      UniProtKB/TrEMBL
      A0A5S9XCZ7, A0A654F7N7, A0A7G2ENK4
      Conserved Domains (1) summary
      cd11368
      Location:11 → 272
      RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome

    2. NM_001338017.1 → NP_001319535.1  ribonuclease PH45A [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2H1ZEI6
      Conserved Domains (1) summary
      cd11368
      Location:11 → 214
      RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome

    3. NM_001338018.1 → NP_001327698.1  ribonuclease PH45A [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VEU1, A0A1I9LT43, A0A384LNX5, A0A7G2ENK4

    4. NM_112136.5 → NP_566441.1  ribonuclease PH45A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566441.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LGD7, Q9LDM2
      UniProtKB/TrEMBL
      A0A5S9XCZ7, A0A654F7N7, A0A7G2ENK4
      Conserved Domains (1) summary
      cd11368
      Location:11 → 272
      RNase_PH_RRP45; RRP45 subunit of eukaryotic exosome
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LDM2.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools