U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    UPL6 ubiquitin protein ligase 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820979, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    UPL6
    Official Full Name
    ubiquitin protein ligase 6
    Primary source
    TAIR:AT3G17205
    Locus tag
    AT3G17205
    See related
    Araport:AT3G17205
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ubiquitin protein ligase 6
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See UPL6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    27
    Sequence:
    Chromosome: 3; NC_003074.8 (5873051..5881655)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene heat stable protein 1 Neighboring gene pectin methylesterase inhibitor 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The HECT ubiquitin-protein ligase (UPL) family in Arabidopsis: UPL3 has a specific role in trichome development. Downes BP, et al. Plant J, 2003 Sep. PMID 12969426
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001125176.1
    NM_001202986.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ubiquitin protein ligase 6
    NP_001118648.1
    • ubiquitin protein ligase 6 (UPL6); CONTAINS InterPro DOMAIN/s: HECT (InterPro:IPR000569), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: ubiquitin-protein ligase 7 (TAIR:AT3G53090.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001189915.1
    • ubiquitin protein ligase 6 (UPL6); CONTAINS InterPro DOMAIN/s: HECT (InterPro:IPR000569), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: ubiquitin-protein ligase 7 (TAIR:AT3G53090.2).
    NP_188346.2
    • ubiquitin protein ligase 6 (UPL6); CONTAINS InterPro DOMAIN/s: HECT (InterPro:IPR000569), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: ubiquitin-protein ligase 7 (TAIR:AT3G53090.2); Has 4447 Blast hits to 4367 proteins in 248 species: Archae - 0; Bacteria - 0; Metazoa - 2469; Fungi - 809; Plants - 361; Viruses - 0; Other Eukaryotes - 808 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5873051..5881655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112597.4 → NP_188346.2  ubiquitin protein ligase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188346.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RWB8, Q9LUV3
      UniProtKB/TrEMBL
      A0A5S9XCX5, A0A654FDD0
      Conserved Domains (1) summary
      cd00078
      Location:667 → 1027
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    2. NM_001202986.1 → NP_001189915.1  ubiquitin protein ligase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189915.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RWB8, Q9LUV3
      UniProtKB/TrEMBL
      A0A5S9XCX5, A0A654FDD0
      Conserved Domains (1) summary
      cd00078
      Location:667 → 1027
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    3. NM_001125176.1 → NP_001118648.1  ubiquitin protein ligase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118648.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H5A6
      Conserved Domains (2) summary
      smart00119
      Location:677 → 1012
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      cd00078
      Location:653 → 1013
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RWB8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools