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    uraH hydroxyisourate hydrolase [ Burkholderia orbicola MC0-3 ]

    Gene ID: 83048758, updated on 24-Jul-2023

    Summary

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    Gene symbol
    uraH
    Gene description
    hydroxyisourate hydrolase
    Locus tag
    BCENMC03_RS09990
    Gene type
    protein coding
    Organism
    Burkholderia orbicola MC0-3 (strain: MC0-3)
    Lineage
    Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; Burkholderia cepacia complex; Burkholderia orbicola
    Old locus tag
    Bcenmc03_1981
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    Genomic context

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    Location:
    chromosome: 1
    Sequence:
    Chromosome: 1; NC_010508.1 (2205873..2206226)

    Chromosome 1 - NC_010508.1Genomic Context describing neighboring genes Neighboring gene LysR substrate-binding domain-containing protein Neighboring gene 8-oxoguanine deaminase Neighboring gene urate hydroxylase PuuD Neighboring gene ACT domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_010508.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and kinetic insights into the mechanism of 5-hydroxyisourate hydrolase from Klebsiella pneumoniae. French JB, et al. Acta Crystallogr D Biol Crystallogr, 2011 Aug. PMID 21795808, Free PMC Article
    2. Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction. Lee Y, et al. Mol Cells, 2006 Oct 31. PMID 17085964
    3. Transthyretin-related proteins function to facilitate the hydrolysis of 5-hydroxyisourate, the end product of the uricase reaction. Lee Y, et al. FEBS Lett, 2005 Aug 29. PMID 16098976

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    hydroxyisourate hydrolase
    WP_011549584.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_010508.1 Reference assembly

      Range
      2205873..2206226
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011549584.1 MULTISPECIES: hydroxyisourate hydrolase [Burkholderia]

      See identical proteins and their annotated locations for WP_011549584.1

      UniProtKB/TrEMBL
      A0A0H2Y1Y8, A0A107L5E4, A0A228HYV7, B1JTY5
      Conserved Domains (1) summary
      COG2351
      Location:1 → 117
      HiuH; 5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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