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    VPS63 Vps63p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850965, updated on 9-Dec-2024

    Summary

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    Official Symbol
    VPS63
    Official Full Name
    Vps63p
    Primary source
    SGD:S000004251
    Locus tag
    YLR261C
    See related
    AllianceGenome:SGD:S000004251; FungiDB:YLR261C; VEuPathDB:YLR261C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in protein targeting to vacuole. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See VPS63 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (668237..668563, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene chaperone ATPase HSP60 Neighboring gene sphinganine kinase LCB5 Neighboring gene Rab family GTPase YPT6 Neighboring gene Tma7p Neighboring gene Red1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasmodium falciparum enolase complements yeast enolase functions and associates with the parasite food vacuole. Das S, et al. Mol Biochem Parasitol, 2011 Sep. PMID 21600245, Free PMC Article
    2. Prevacuolar compartment morphology in vps mutants of Saccharomyces cerevisiae. Hedman JM, et al. Cell Biol Int, 2007 Oct. PMID 17543551
    3. Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Bonangelino CJ, et al. Mol Biol Cell, 2002 Jul. PMID 12134085, Free PMC Article
    4. Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. Viladevall L, et al. J Biol Chem, 2004 Oct 15. PMID 15299026
    5. Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Gustavsson M, et al. Mol Genet Genomics, 2008 Sep. PMID 18612650

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein targeting to vacuole HMP PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Vps63p
    NP_013362.1
    • hypothetical protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene YPT6; deletion causes a vacuolar protein sorting defect; decreased levels of protein in enolase deficient mutant

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      668237..668563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182148.1 → NP_013362.1  TPA: Vps63p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013362.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0B7P1T6, O13549
      UniProtKB/TrEMBL
      C8ZDM4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O13549.1

    Gene LinkOut

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    Research Materials