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    FUN19 Fun19p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851199, updated on 9-Dec-2024

    Summary

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    Official Symbol
    FUN19
    Official Full Name
    Fun19p
    Primary source
    SGD:S000002134
    Locus tag
    YAL034C
    See related
    AllianceGenome:SGD:S000002134; FungiDB:YAL034C; VEuPathDB:YAL034C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable chromatin binding activity and transcription coactivator activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be part of Rpd3L-Expanded complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See FUN19 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_001133.9 (80710..81951, complement)

    Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene translation initiation factor eIF5B Neighboring gene MIND complex subunit MTW1 Neighboring gene RNA-binding protein POP5 Neighboring gene mRNA splicing protein PRP45

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001133.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular analysis of Saccharomyces cerevisiae chromosome I. On the number of genes and the identification of essential genes using temperature-sensitive-lethal mutations. Harris SD, et al. J Mol Biol, 1992 May 5. PMID 1583694
    2. Molecular analysis of Saccharomyces cerevisiae chromosome I: identification of additional transcribed regions and demonstration that some encode essential functions. Diehl BE, et al. Genetics, 1991 Feb. PMID 1825988, Free PMC Article
    3. Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. Sakaki K, et al. J Biochem, 2003 Sep. PMID 14561723
    4. Coupling protein complex analysis to peptide based proteomics. Gao Q, et al. J Chromatogr A, 2010 Dec 3. PMID 21036361
    5. The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. Bussey H, et al. Proc Natl Acad Sci U S A, 1995 Apr 25. PMID 7731988, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Rpd3L-Expanded complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Fun19p
    NP_009368.2
    • Non-essential hypothetical protein; expression induced in response to heat stress; FUN19 has a paralog, YOR338W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001133.9 Reference assembly

      Range
      80710..81951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180035.1 → NP_009368.2  TPA: Fun19p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009368.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VPI4, P28003
      UniProtKB/TrEMBL
      A7A0D4, B3LUW8, C7GPK1, C8Z3F9, G2W8J8, N1P8V8
      Conserved Domains (1) summary
      pfam04433
      Location:331 → 409
      SWIRM; SWIRM domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P28003.3

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