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    VAM10 Vam10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854234, updated on 9-Dec-2024

    Summary

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    Official Symbol
    VAM10
    Official Full Name
    Vam10p
    Primary source
    SGD:S000005594
    Locus tag
    YOR068C
    See related
    AllianceGenome:SGD:S000005594; FungiDB:YOR068C; VEuPathDB:YOR068C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in vacuole fusion, non-autophagic. Predicted to be located in fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See VAM10 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (453869..454213, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Msa1p Neighboring gene dolichyl-P-Glc:Glc1Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase Neighboring gene sorting nexin 1 Neighboring gene GTPase-activating protein GYP1 Neighboring gene nicotinamide riboside transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vam10p defines a Sec18p-independent step of priming that allows yeast vacuole tethering. Kato M, et al. Proc Natl Acad Sci U S A, 2003 May 27. PMID 12748377, Free PMC Article
    2. Synthetic dosage lethal (SDL) interaction data of Hmt1 arginine methyltransferase. Kyriakou D, et al. Data Brief, 2020 Aug. PMID 32637492, Free PMC Article
    3. Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Chen Y, et al. Mol Cancer Res, 2005 Dec. PMID 16380504
    4. A Genome-Wide Screen with Nicotinamide to Identify Sirtuin-Dependent Pathways in Saccharomyces cerevisiae. Choy JS, et al. G3 (Bethesda), 2015 Dec 8. PMID 26646153, Free PMC Article
    5. Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae. Mulder KW, et al. Genetics, 2007 May. PMID 17513889, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in vacuole fusion, non-autophagic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in fungal-type vacuole membrane IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Vam10p
    NP_014711.1
    • Protein involved in vacuole morphogenesis; acts at an early step of homotypic vacuole fusion that is required for vacuole tethering

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      453869..454213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183487.1 → NP_014711.1  TPA: Vam10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014711.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2D2, O00027, Q08474
      UniProtKB/TrEMBL
      A6ZNS1, B3LJB8, C7GX50, C8ZI30, G2WMU7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08474.1

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