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    BSC5 Bsc5p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855806, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BSC5
    Official Full Name
    Bsc5p
    Primary source
    SGD:S000005352
    Locus tag
    YNR069C
    See related
    AllianceGenome:SGD:S000005352; FungiDB:YNR069C; VEuPathDB:YNR069C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    BUL3
    Summary
    Predicted to enable ubiquitin-ubiquitin ligase activity. Predicted to be involved in protein monoubiquitination and protein polyubiquitination. Predicted to be part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See BSC5 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (761123..762592, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene endo-1,3(4)-beta-glucanase Neighboring gene uncharacterized protein Neighboring gene ATP-binding cassette multidrug transporter PDR18 Neighboring gene aldose 1-epimerase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quality control of plasma membrane proteins by Saccharomyces cerevisiae Nedd4-like ubiquitin ligase Rsp5p under environmental stress conditions. Shiga T, et al. Eukaryot Cell, 2014 Sep. PMID 25001409, Free PMC Article
    2. Bul proteins, a nonredundant, antagonistic family of ubiquitin ligase regulatory proteins. Novoselova TV, et al. Eukaryot Cell, 2012 Apr. PMID 22307975, Free PMC Article
    3. Identification of stop codon readthrough genes in Saccharomyces cerevisiae. Namy O, et al. Nucleic Acids Res, 2003 May 1. PMID 12711673, Free PMC Article
    4. Direct in vivo access to potential gene targets of the RPD3 histone deactylase using fitness-based interferential genetics. Daniel J. Yeast, 2007 Jul. PMID 17533620
    5. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Gupta R, et al. Mol Syst Biol, 2007. PMID 17551511, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables ubiquitin-ubiquitin ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in protein monoubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Bsc5p
    NP_014467.3
    • hypothetical protein; shows homology with N-terminal end of Bul1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough expression includes YNR068C and the locus for this readthrough is termed BUL3; Bul3p is involved in ubiquitin-mediated sorting of plasma membrane proteins; readthrough and shortened forms of Bul3p interact with Rsp5p differently in vitro

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      761123..762592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183246.3 → NP_014467.3  TPA: Bsc5p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014467.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1P4, P53755, Q66R20
      UniProtKB/TrEMBL
      B3LPH5
      Conserved Domains (1) summary
      pfam04425
      Location:58 → 462
      Bul1_N; Bul1 N-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53755.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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