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    RGV86_RS18290 tRNA 4-thiouridine(8) synthase ThiI [ Escherichia ruysiae ]

    Gene ID: 86862968, updated on 3-Dec-2024

    Summary

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    Gene symbol
    RGV86_RS18290
    Gene description
    tRNA 4-thiouridine(8) synthase ThiI
    Locus tag
    RGV86_RS18290
    Gene type
    protein coding
    Organism
    Escherichia ruysiae (strain: AB136, nat-host: Canis lupus familiaris)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Old locus tag
    RGV86_18290
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    Genomic context

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    NZ_JAVIWS0100000.1Genomic Context describing neighboring genes Neighboring gene (2E,6E)-farnesyl diphosphate synthase Neighboring gene exodeoxyribonuclease VII small subunit Neighboring gene protein deglycase YajL Neighboring gene 2-dehydropantoate 2-reductase Neighboring gene nucleotide binding protein YajQ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_JAVIWS010000001.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Direct evidence that ThiI is an ATP pyrophosphatase for the adenylation of uridine in 4-thiouridine biosynthesis. You D, et al. Chembiochem, 2008 Aug 11. PMID 18604845
    2. The role of the cysteine residues of ThiI in the generation of 4-thiouridine in tRNA. Mueller EG, et al. J Biol Chem, 2001 Sep 7. PMID 11443125
    3. Characterization of thiI, a new gene involved in thiazole biosynthesis in Salmonella typhimurium. Webb E, et al. J Bacteriol, 1997 Jul. PMID 9209060, Free PMC Article
    4. The rhodanese domain of ThiI is both necessary and sufficient for synthesis of the thiazole moiety of thiamine in Salmonella enterica. Martinez-Gomez NC, et al. J Bacteriol, 2011 Sep. PMID 21724998, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    tRNA 4-thiouridine(8) synthase ThiI
    WP_000668662.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_JAVIWS010000001.1 Reference assembly

      Range
      3797039..3798487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_000668662.1 MULTISPECIES: tRNA 4-thiouridine(8) synthase ThiI [Enterobacteriaceae]

      See identical proteins and their annotated locations for WP_000668662.1

      UniProtKB/Swiss-Prot
      B1XF11, B7N8X6, C4ZTI0, P77718, Q2MC03
      UniProtKB/TrEMBL
      A0A037Y6G8, A0A1X3IB22, A0A7Z8FG51, A0AAJ3NZN9