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    mbtN acyl-[acyl-carrier-protein] dehydrogenase MbtN [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886844, updated on 6-Oct-2023

    Summary

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    Gene symbol
    mbtN
    Gene description
    acyl-[acyl-carrier-protein] dehydrogenase MbtN
    Locus tag
    Rv1346
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Also known as
    fadE14
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    Genomic context

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    Sequence:
    NC_000962.3 (1510846..1512006)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene lipoprotein LprD Neighboring gene acyl carrier protein MbtL Neighboring gene long-chain-fatty-acid--ACP ligase MbtM Neighboring gene lysine N-acetyltransferase MbtK Neighboring gene tRNA-Leu Neighboring gene iron ABC transporter ATP-binding protein/permease IrtA Neighboring gene iron ABC transporter ATP-binding protein/permease IrtB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket. Chai AF, et al. Acta Crystallogr D Biol Crystallogr, 2015 Apr. PMID 25849397
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The crystal structure of an Mycobacterium tuberculosis enzyme involved in mycobactin biosynthesis, MbtN, in complex with its FAD cofactor is presented at 2.30 A resolution.
      Title: A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    acyl-[acyl-carrier-protein] dehydrogenase MbtN

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      1510846..1512006
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_215862.1 acyl-ACP dehydrogenase MbtN [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_215862.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A916L7D5
      Conserved Domains (1) summary
      NF037942
      Location:6 → 381
      ac_ACP_DH_MbtN; mycobactin biosynthesis acyl-ACP dehydrogenase MbtN
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WQF9.1

    Gene LinkOut

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    Molecular Biology Databases