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    sufC Fe-S cluster scaffold complex subunit SufC [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946128, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sufC
    Official Full Name
    Fe-S cluster scaffold complex subunit SufC
    Primary source
    ECOCYC:G6908
    Locus tag
    b1682
    See related
    ASAP:ABE-0005619
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1678; ynhD
    Summary
    SufC is part of the protein machinery that is involved in the biosynthesis of iron-sulfur clusters. [More information is available at EcoCyc: G6908].
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    Genomic context

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    Sequence:
    NC_000913.3 (1761766..1762512, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene sulfur carrier protein SufE Neighboring gene L-cysteine desulfurase Neighboring gene Fe-S cluster scaffold complex subunit SufD Neighboring gene Fe-S cluster scaffold complex subunit SufB Neighboring gene iron-sulfur cluster insertion protein SufA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SufC hydrolyzes ATP and interacts with SufB from Thermotoga maritima. Rangachari K, et al. FEBS Lett, 2002 Mar 13. PMID 11943156
    2. Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor. Wollers S, et al. J Biol Chem, 2010 Jul 23. PMID 20460376, Free PMC Article
    3. Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex. Wada K, et al. J Mol Biol, 2009 Mar 20. PMID 19361433, Free PMC Article
    4. The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer. Chahal HK, et al. Biochemistry, 2009 Nov 10. PMID 19810706, Free PMC Article
    5. Induction of the sufA operon encoding Fe-S assembly proteins by superoxide generators and hydrogen peroxide: involvement of OxyR, IHF and an unidentified oxidant-responsive factor. Lee JH, et al. Mol Microbiol, 2004 Mar. PMID 15009899

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within iron-sulfur cluster assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in iron-sulfur cluster assembly NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to radiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of iron-sulfur cluster assembly complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of iron-sulfur cluster assembly complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Fe-S cluster scaffold complex subunit SufC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1761766..1762512 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416197.1 Fe-S cluster scaffold complex subunit SufC [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416197.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7Y4N5
      Conserved Domains (1) summary
      PRK09580
      Location:1 → 248
      sufC; cysteine desulfurase ATPase component; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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