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    nac DNA-binding transcriptional dual regulator Nac [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946501, updated on 17-Dec-2024

    Summary

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    Official Symbol
    nac
    Official Full Name
    DNA-binding transcriptional dual regulator Nac
    Primary source
    ECOCYC:G7072
    Locus tag
    b1988
    See related
    ASAP:ABE-0006594
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1983
    Summary
    LysR family. [More information is available at EcoGene: EG14265]. Nac, "nitrogen assimilation control," regulates, without a coeffector, genes involved in nitrogen metabolism under nitrogen-limiting conditions . [More information is available at EcoCyc: G7072].
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    Genomic context

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    Sequence:
    NC_000913.3 (2061016..2061933, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Asn Neighboring gene DNA-binding transcriptional activator Cbl Neighboring gene tRNA-Asn Neighboring gene L,D-transpeptidase LdtA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The amino-terminal 100 residues of the nitrogen assimilation control protein (NAC) encode all known properties of NAC from Klebsiella aerogenes and Escherichia coli. Muse WB, et al. J Bacteriol, 1999 Feb. PMID 9922258, Free PMC Article
    2. The nac (nitrogen assimilation control) gene from Escherichia coli. Muse WB, et al. J Bacteriol, 1998 Mar. PMID 9495755, Free PMC Article
    3. Nac-mediated repression of the serA promoter of Escherichia coli. Blauwkamp TA, et al. Mol Microbiol, 2002 Jul. PMID 12123449
    4. Transcriptional repression of gdhA in Escherichia coli is mediated by the Nac protein. Camarena L, et al. FEMS Microbiol Lett, 1998 Oct 1. PMID 9785451
    5. Nitrogen regulation of the codBA (cytosine deaminase) operon from Escherichia coli by the nitrogen assimilation control protein, NAC. Muse WB, et al. J Bacteriol, 2003 May. PMID 12700271, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nitrate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional dual regulator Nac

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2061016..2061933 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416493.1 DNA-binding transcriptional dual regulator Nac [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416493.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376M6F0
      Conserved Domains (1) summary
      PRK11233
      Location:1 → 305
      PRK11233; nitrogen assimilation transcriptional regulator; Provisional
    Nucleotide Protein
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