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    truC tRNA pseudouridine(65) synthase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947242, updated on 17-Dec-2024

    Summary

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    Official Symbol
    truC
    Official Full Name
    tRNA pseudouridine(65) synthase
    Primary source
    ECOCYC:G7449
    Locus tag
    b2791
    See related
    ASAP:ABE-0009147
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2785; yqcB
    Summary
    TruC is the pseudouridine synthase that catalyzes formation of pseudouridine at position 65 in tRNAIle1 and tRNAAsp. [More information is available at EcoCyc: G7449].
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    Genomic context

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    Sequence:
    NC_000913.3 (2923002..2923784, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene galactarate/D-glucarate transporter GudP Neighboring gene putative flavodoxin YqcA Neighboring gene DUF446 domain-containing protein YqcC Neighboring gene ncRNA Neighboring gene SecY-interacting protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. Del Campo M, et al. RNA, 2001 Nov. PMID 11720289, Free PMC Article
    2. Protein abundance profiling of the Escherichia coli cytosol. Ishihama Y, et al. BMC Genomics, 2008 Feb 27. PMID 18304323, Free PMC Article
    3. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
    4. Pseudouridine synthases. Hamma T, et al. Chem Biol, 2006 Nov. PMID 17113994
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity, acting on RNA IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables tRNA pseudouridine synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables tRNA pseudouridine(65) synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in enzyme-directed rRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within tRNA pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA pseudouridine(65) synthase
    NP_417271.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2923002..2923784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417271.1 tRNA pseudouridine(65) synthase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417271.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A444REG8
      Conserved Domains (1) summary
      PRK11112
      Location:1 → 255
      PRK11112; tRNA pseudouridine synthase C; Provisional
    Nucleotide Protein
    Heading Accession and Version

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