Name: rs35504374
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs35504374

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr7:77691625-77691645 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: del(A)₁₃ / del(A)₁₁ / del(A)₇ / de…
del(A)₁₃ / del(A)₁₁ / del(A)₇ / del(A)₆ / del(A)₅ / del(A)₄ / delAAA / delAA / delA / dupA / dupAA / dupAAA
Variation Type: Indel Insertion and Deletion
Frequency: delAA=0.1277 (1021/7993, ALFA)
delAA=0.4477 (2242/5008, 1000G)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: APTR : Intron Variant
Publications: 0 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	Alt HMOZ	HTRZ	HWEP
Total	Global	7993	AAAAAAAAAAAAAAAAAAAAA=0.8649	AAAAAAAA=0.0000, AAAAAAAAAA=0.0000, AAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAAAAA=0.0036, AAAAAAAAAAAAAAAAAAA=0.1277, AAAAAAAAAAAAAAAAAAAAAA=0.0038, AAAAAAAAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAAAAAAAAAA=0.0000	0.778405	0.035137	0.186458	32
European	Sub	7133	AAAAAAAAAAAAAAAAAAAAA=0.8489	AAAAAAAA=0.0000, AAAAAAAAAA=0.0000, AAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAAAAA=0.0041, AAAAAAAAAAAAAAAAAAA=0.1429, AAAAAAAAAAAAAAAAAAAAAA=0.0042, AAAAAAAAAAAAAAAAAAAA=0.0000, AAAAAAAAAAAAAAAAAAAAAAA=0.0000	0.751225	0.039204	0.20957	32
African	Sub	294	AAAAAAAAAAAAAAAAAAAAA=1.000	AAAAAAAA=0.000, AAAAAAAAAA=0.000, AAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAAA=0.000	1.0	0.0	0.0	N/A
African Others	Sub	8	AAAAAAAAAAAAAAAAAAAAA=1.0	AAAAAAAA=0.0, AAAAAAAAAA=0.0, AAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAAAAAAA=0.0, AAAAAAAAAAAAAAAAAAAAAAA=0.0	1.0	0.0	0.0	N/A
African American	Sub	286	AAAAAAAAAAAAAAAAAAAAA=1.000	AAAAAAAA=0.000, AAAAAAAAAA=0.000, AAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAAA=0.000	1.0	0.0	0.0	N/A
Asian	Sub	62	AAAAAAAAAAAAAAAAAAAAA=1.00	AAAAAAAA=0.00, AAAAAAAAAA=0.00, AAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAAA=0.00	1.0	0.0	0.0	N/A
East Asian	Sub	44	AAAAAAAAAAAAAAAAAAAAA=1.00	AAAAAAAA=0.00, AAAAAAAAAA=0.00, AAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAAA=0.00	1.0	0.0	0.0	N/A
Other Asian	Sub	18	AAAAAAAAAAAAAAAAAAAAA=1.00	AAAAAAAA=0.00, AAAAAAAAAA=0.00, AAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAAA=0.00	1.0	0.0	0.0	N/A
Latin American 1	Sub	54	AAAAAAAAAAAAAAAAAAAAA=1.00	AAAAAAAA=0.00, AAAAAAAAAA=0.00, AAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAAA=0.00	1.0	0.0	0.0	N/A
Latin American 2	Sub	276	AAAAAAAAAAAAAAAAAAAAA=1.000	AAAAAAAA=0.000, AAAAAAAAAA=0.000, AAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAAA=0.000	1.0	0.0	0.0	N/A
South Asian	Sub	20	AAAAAAAAAAAAAAAAAAAAA=1.00	AAAAAAAA=0.00, AAAAAAAAAA=0.00, AAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAA=0.00, AAAAAAAAAAAAAAAAAAAAAAA=0.00	1.0	0.0	0.0	N/A
Other	Sub	154	AAAAAAAAAAAAAAAAAAAAA=0.987	AAAAAAAA=0.000, AAAAAAAAAA=0.000, AAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAA=0.013, AAAAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAA=0.000, AAAAAAAAAAAAAAAAAAAAAAA=0.000	0.987013	0.012987	0.0	32

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download

Study	Population	Group	Sample Size	Ref Allele	Alt Allele
Allele Frequency Aggregator	Total	Global	7993	(A)₂₁=0.8649	del(A)₁₃=0.0000, del(A)₁₁=0.0000, del(A)₇=0.0000, del(A)₆=0.0000, del(A)₄=0.0000, delAAA=0.0036, delAA=0.1277, delA=0.0000, dupA=0.0038, dupAA=0.0000
Allele Frequency Aggregator	European	Sub	7133	(A)₂₁=0.8489	del(A)₁₃=0.0000, del(A)₁₁=0.0000, del(A)₇=0.0000, del(A)₆=0.0000, del(A)₄=0.0000, delAAA=0.0041, delAA=0.1429, delA=0.0000, dupA=0.0042, dupAA=0.0000
Allele Frequency Aggregator	African	Sub	294	(A)₂₁=1.000	del(A)₁₃=0.000, del(A)₁₁=0.000, del(A)₇=0.000, del(A)₆=0.000, del(A)₄=0.000, delAAA=0.000, delAA=0.000, delA=0.000, dupA=0.000, dupAA=0.000
Allele Frequency Aggregator	Latin American 2	Sub	276	(A)₂₁=1.000	del(A)₁₃=0.000, del(A)₁₁=0.000, del(A)₇=0.000, del(A)₆=0.000, del(A)₄=0.000, delAAA=0.000, delAA=0.000, delA=0.000, dupA=0.000, dupAA=0.000
Allele Frequency Aggregator	Other	Sub	154	(A)₂₁=0.987	del(A)₁₃=0.000, del(A)₁₁=0.000, del(A)₇=0.000, del(A)₆=0.000, del(A)₄=0.000, delAAA=0.000, delAA=0.013, delA=0.000, dupA=0.000, dupAA=0.000
Allele Frequency Aggregator	Asian	Sub	62	(A)₂₁=1.00	del(A)₁₃=0.00, del(A)₁₁=0.00, del(A)₇=0.00, del(A)₆=0.00, del(A)₄=0.00, delAAA=0.00, delAA=0.00, delA=0.00, dupA=0.00, dupAA=0.00
Allele Frequency Aggregator	Latin American 1	Sub	54	(A)₂₁=1.00	del(A)₁₃=0.00, del(A)₁₁=0.00, del(A)₇=0.00, del(A)₆=0.00, del(A)₄=0.00, delAAA=0.00, delAA=0.00, delA=0.00, dupA=0.00, dupAA=0.00
Allele Frequency Aggregator	South Asian	Sub	20	(A)₂₁=1.00	del(A)₁₃=0.00, del(A)₁₁=0.00, del(A)₇=0.00, del(A)₆=0.00, del(A)₄=0.00, delAAA=0.00, delAA=0.00, delA=0.00, dupA=0.00, dupAA=0.00
1000Genomes	Global	Study-wide	5008	(A)₂₁=0.5523	delAA=0.4477
1000Genomes	African	Sub	1322	(A)₂₁=0.3343	delAA=0.6657
1000Genomes	East Asian	Sub	1008	(A)₂₁=0.7669	delAA=0.2331
1000Genomes	Europe	Sub	1006	(A)₂₁=0.6113	delAA=0.3887
1000Genomes	South Asian	Sub	978	(A)₂₁=0.475	delAA=0.525
1000Genomes	American	Sub	694	(A)₂₁=0.679	delAA=0.321

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 7	NC_000007.14:g.77691633_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691635_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691639_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691640_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691641_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691642_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691643_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691644_77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691645del
GRCh38.p14 chr 7	NC_000007.14:g.77691645dup
GRCh38.p14 chr 7	NC_000007.14:g.77691644_77691645dup
GRCh38.p14 chr 7	NC_000007.14:g.77691643_77691645dup
GRCh37.p13 chr 7	NC_000007.13:g.77320950_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320952_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320956_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320957_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320958_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320959_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320960_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320961_77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320962del
GRCh37.p13 chr 7	NC_000007.13:g.77320962dup
GRCh37.p13 chr 7	NC_000007.13:g.77320961_77320962dup
GRCh37.p13 chr 7	NC_000007.13:g.77320960_77320962dup

Gene: APTR, Alu-mediated CDKN1A/p21 transcriptional regulator (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
APTR transcript variant 1	NR_038361.1:n.	N/A	Intron Variant
APTR transcript variant 2	NR_134251.1:n.	N/A	Intron Variant
APTR transcript variant 3	NR_134253.1:n.	N/A	Intron Variant
APTR transcript variant 4	NR_134254.1:n.	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	(A)₂₁=	del(A)₁₃	del(A)₁₁	del(A)₇	del(A)₆	del(A)₅	del(A)₄	delAAA	delAA	delA	dupA	dupAA	dupAAA
GRCh38.p14 chr 7	NC_000007.14:g.77691625_77691645=	NC_000007.14:g.77691633_77691645del	NC_000007.14:g.77691635_77691645del	NC_000007.14:g.77691639_77691645del	NC_000007.14:g.77691640_77691645del	NC_000007.14:g.77691641_77691645del	NC_000007.14:g.77691642_77691645del	NC_000007.14:g.77691643_77691645del	NC_000007.14:g.77691644_77691645del	NC_000007.14:g.77691645del	NC_000007.14:g.77691645dup	NC_000007.14:g.77691644_77691645dup	NC_000007.14:g.77691643_77691645dup
GRCh37.p13 chr 7	NC_000007.13:g.77320942_77320962=	NC_000007.13:g.77320950_77320962del	NC_000007.13:g.77320952_77320962del	NC_000007.13:g.77320956_77320962del	NC_000007.13:g.77320957_77320962del	NC_000007.13:g.77320958_77320962del	NC_000007.13:g.77320959_77320962del	NC_000007.13:g.77320960_77320962del	NC_000007.13:g.77320961_77320962del	NC_000007.13:g.77320962del	NC_000007.13:g.77320962dup	NC_000007.13:g.77320961_77320962dup	NC_000007.13:g.77320960_77320962dup

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

53 SubSNP, 28 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	ABI	ss42923742	Mar 15, 2006 (126)
2	HGSV	ss82358348	Dec 15, 2007 (129)
3	HGSV	ss82704302	Dec 15, 2007 (129)
4	HGSV	ss83899211	Dec 15, 2007 (129)
5	BCMHGSC_JDW	ss103752514	Mar 15, 2016 (147)
6	BILGI_BIOE	ss666404386	Apr 25, 2013 (138)
7	1000GENOMES	ss1377267328	Jan 10, 2018 (151)
8	EVA_UK10K_ALSPAC	ss1705690900	Apr 01, 2015 (144)
9	EVA_UK10K_TWINSUK	ss1705690993	Apr 01, 2015 (144)
10	EVA_UK10K_ALSPAC	ss1710331604	Apr 01, 2015 (144)
11	EVA_UK10K_TWINSUK	ss1710337223	Apr 01, 2015 (144)
12	SWEGEN	ss3001466223	Nov 08, 2017 (151)
13	MCHAISSO	ss3066152217	Jan 10, 2018 (151)
14	EVA_DECODE	ss3720012145	Jul 13, 2019 (153)
15	EVA_DECODE	ss3720012146	Jul 13, 2019 (153)
16	EVA_DECODE	ss3720012147	Jul 13, 2019 (153)
17	EVA_DECODE	ss3720012148	Jul 13, 2019 (153)
18	EVA_DECODE	ss3720012149	Jul 13, 2019 (153)
19	EVA_DECODE	ss3720012150	Jul 13, 2019 (153)
20	KHV_HUMAN_GENOMES	ss3809914216	Jul 13, 2019 (153)
21	EVA	ss3830650188	Apr 26, 2020 (154)
22	EVA	ss3838821642	Apr 26, 2020 (154)
23	KOGIC	ss3961901444	Apr 26, 2020 (154)
24	KOGIC	ss3961901445	Apr 26, 2020 (154)
25	KOGIC	ss3961901446	Apr 26, 2020 (154)
26	KOGIC	ss3961901447	Apr 26, 2020 (154)
27	GNOMAD	ss4166677442	Apr 26, 2021 (155)
28	GNOMAD	ss4166677443	Apr 26, 2021 (155)
29	GNOMAD	ss4166677444	Apr 26, 2021 (155)
30	GNOMAD	ss4166677445	Apr 26, 2021 (155)
31	GNOMAD	ss4166677446	Apr 26, 2021 (155)
32	GNOMAD	ss4166677447	Apr 26, 2021 (155)
33	GNOMAD	ss4166677448	Apr 26, 2021 (155)
34	GNOMAD	ss4166677449	Apr 26, 2021 (155)
35	GNOMAD	ss4166677450	Apr 26, 2021 (155)
36	GNOMAD	ss4166677451	Apr 26, 2021 (155)
37	TOMMO_GENOMICS	ss5183976085	Apr 26, 2021 (155)
38	TOMMO_GENOMICS	ss5183976086	Apr 26, 2021 (155)
39	TOMMO_GENOMICS	ss5183976087	Apr 26, 2021 (155)
40	1000G_HIGH_COVERAGE	ss5273504924	Oct 17, 2022 (156)
41	1000G_HIGH_COVERAGE	ss5273504925	Oct 17, 2022 (156)
42	1000G_HIGH_COVERAGE	ss5273504926	Oct 17, 2022 (156)
43	1000G_HIGH_COVERAGE	ss5273504927	Oct 17, 2022 (156)
44	HUGCELL_USP	ss5470524864	Oct 17, 2022 (156)
45	HUGCELL_USP	ss5470524865	Oct 17, 2022 (156)
46	HUGCELL_USP	ss5470524866	Oct 17, 2022 (156)
47	HUGCELL_USP	ss5470524867	Oct 17, 2022 (156)
48	EVA	ss5509010340	Oct 17, 2022 (156)
49	TOMMO_GENOMICS	ss5724486097	Oct 17, 2022 (156)
50	TOMMO_GENOMICS	ss5724486098	Oct 17, 2022 (156)
51	TOMMO_GENOMICS	ss5724486099	Oct 17, 2022 (156)
52	TOMMO_GENOMICS	ss5724486100	Oct 17, 2022 (156)
53	EVA	ss5855959984	Oct 17, 2022 (156)
54	1000Genomes	NC_000007.13 - 77320942	Oct 12, 2018 (152)
55	The Avon Longitudinal Study of Parents and Children Submission ignored due to conflicting rows: Row 20996406 (NC_000007.13:77320942:A: 2187/3854) Row 20996407 (NC_000007.13:77320941:AAA: 1054/3854)	-	Oct 12, 2018 (152)
56	The Avon Longitudinal Study of Parents and Children Submission ignored due to conflicting rows: Row 20996406 (NC_000007.13:77320942:A: 2187/3854) Row 20996407 (NC_000007.13:77320941:AAA: 1054/3854)	-	Oct 12, 2018 (152)
57	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
58	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
59	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
60	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
61	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
62	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
63	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
64	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
65	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
66	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
67	gnomAD - Genomes Submission ignored due to conflicting rows: Row 266165447 (NC_000007.14:77691624::A 963/89348) Row 266165448 (NC_000007.14:77691624::AA 4/89570) Row 266165449 (NC_000007.14:77691624::AAA 1/89586)...	-	Apr 26, 2021 (155)
68	Korean Genome Project Submission ignored due to conflicting rows: Row 18279445 (NC_000007.14:77691626:A: 253/1812) Row 18279446 (NC_000007.14:77691627::A 120/1812) Row 18279447 (NC_000007.14:77691625:AA: 376/1812)...	-	Apr 26, 2020 (154)
69	Korean Genome Project Submission ignored due to conflicting rows: Row 18279445 (NC_000007.14:77691626:A: 253/1812) Row 18279446 (NC_000007.14:77691627::A 120/1812) Row 18279447 (NC_000007.14:77691625:AA: 376/1812)...	-	Apr 26, 2020 (154)
70	Korean Genome Project Submission ignored due to conflicting rows: Row 18279445 (NC_000007.14:77691626:A: 253/1812) Row 18279446 (NC_000007.14:77691627::A 120/1812) Row 18279447 (NC_000007.14:77691625:AA: 376/1812)...	-	Apr 26, 2020 (154)
71	Korean Genome Project Submission ignored due to conflicting rows: Row 18279445 (NC_000007.14:77691626:A: 253/1812) Row 18279446 (NC_000007.14:77691627::A 120/1812) Row 18279447 (NC_000007.14:77691625:AA: 376/1812)...	-	Apr 26, 2020 (154)
72	8.3KJPN Submission ignored due to conflicting rows: Row 41945392 (NC_000007.13:77320941:A: 32/16616) Row 41945393 (NC_000007.13:77320941:AA: 4523/16616) Row 41945394 (NC_000007.13:77320941::A 238/16616)	-	Apr 26, 2021 (155)
73	8.3KJPN Submission ignored due to conflicting rows: Row 41945392 (NC_000007.13:77320941:A: 32/16616) Row 41945393 (NC_000007.13:77320941:AA: 4523/16616) Row 41945394 (NC_000007.13:77320941::A 238/16616)	-	Apr 26, 2021 (155)
74	8.3KJPN Submission ignored due to conflicting rows: Row 41945392 (NC_000007.13:77320941:A: 32/16616) Row 41945393 (NC_000007.13:77320941:AA: 4523/16616) Row 41945394 (NC_000007.13:77320941::A 238/16616)	-	Apr 26, 2021 (155)
75	14KJPN Submission ignored due to conflicting rows: Row 58323201 (NC_000007.14:77691624:AA: 8070/28174) Row 58323202 (NC_000007.14:77691624::A 353/28174) Row 58323203 (NC_000007.14:77691624:A: 40/28174)...	-	Oct 17, 2022 (156)
76	14KJPN Submission ignored due to conflicting rows: Row 58323201 (NC_000007.14:77691624:AA: 8070/28174) Row 58323202 (NC_000007.14:77691624::A 353/28174) Row 58323203 (NC_000007.14:77691624:A: 40/28174)...	-	Oct 17, 2022 (156)
77	14KJPN Submission ignored due to conflicting rows: Row 58323201 (NC_000007.14:77691624:AA: 8070/28174) Row 58323202 (NC_000007.14:77691624::A 353/28174) Row 58323203 (NC_000007.14:77691624:A: 40/28174)...	-	Oct 17, 2022 (156)
78	14KJPN Submission ignored due to conflicting rows: Row 58323201 (NC_000007.14:77691624:AA: 8070/28174) Row 58323202 (NC_000007.14:77691624::A 353/28174) Row 58323203 (NC_000007.14:77691624:A: 40/28174)...	-	Oct 17, 2022 (156)
79	UK 10K study - Twins Submission ignored due to conflicting rows: Row 20996406 (NC_000007.13:77320942:A: 2118/3708) Row 20996407 (NC_000007.13:77320941:AAA: 945/3708)	-	Oct 12, 2018 (152)
80	UK 10K study - Twins Submission ignored due to conflicting rows: Row 20996406 (NC_000007.13:77320942:A: 2118/3708) Row 20996407 (NC_000007.13:77320941:AAA: 945/3708)	-	Oct 12, 2018 (152)
81	ALFA	NC_000007.14 - 77691625	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs74320658	May 11, 2012 (137)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss4166677451	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAA	(self)
ss4166677450	NC_000007.14:77691624:AAAAAAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAA	(self)
ss4166677449	NC_000007.14:77691624:AAAAAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAA	(self)
ss3720012150, ss4166677448	NC_000007.14:77691624:AAAAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAA	(self)
ss4166677447, ss5855959984	NC_000007.14:77691624:AAAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA	(self)
ss3720012149	NC_000007.14:77691625:AAAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAA	(self)
ss666404386, ss1705690900, ss1705690993, ss3001466223	NC_000007.13:77320941:AAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA	(self)
ss3961901447, ss4166677446, ss5273504926, ss5470524866, ss5724486100	NC_000007.14:77691624:AAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA	(self)
ss3720012148	NC_000007.14:77691626:AAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA	(self)
ss42923742	NT_007933.15:15353802:AAA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAA	(self)
ss82358348, ss82704302, ss83899211	NC_000007.11:76965611:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
37730032, ss1377267328, ss3830650188, ss3838821642, ss5183976086	NC_000007.13:77320941:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
ss1710331604, ss1710337223	NC_000007.13:77320942:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
ss3066152217, ss3809914216, ss4166677445, ss5273504924, ss5470524864, ss5724486097	NC_000007.14:77691624:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
ss3961901446	NC_000007.14:77691625:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
ss3720012147	NC_000007.14:77691627:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
ss103752514	NT_007933.15:15353802:AA:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAA	(self)
ss5183976085	NC_000007.13:77320941:A:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	(self)
	NC_000007.13:77320942:A:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	(self)
ss5273504925, ss5470524867, ss5724486099	NC_000007.14:77691624:A:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	(self)
ss3961901444	NC_000007.14:77691626:A:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	(self)
ss3720012146	NC_000007.14:77691628:A:	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAA	(self)
ss5183976087	NC_000007.13:77320941::A	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA	(self)
ss4166677442, ss5273504927, ss5470524865, ss5724486098	NC_000007.14:77691624::A	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA	(self)
ss3961901445	NC_000007.14:77691627::A	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA	(self)
ss3720012145	NC_000007.14:77691629::A	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAA	(self)
ss5509010340	NC_000007.13:77320941::AA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAA
ss4166677443	NC_000007.14:77691624::AA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAA	(self)
9401470594	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAA	(self)
ss4166677444	NC_000007.14:77691624::AAA	NC_000007.14:77691624:AAAAAAAAAAAA… NC_000007.14:77691624:AAAAAAAAAAAAAAAAAAAAA:AAAAAAAAAAAAAAAAAAAAAAAA	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

No publications for rs35504374

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs35504374