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1.

rs1491459863 has merged into rs59976658 [Homo sapiens]
    Variant type:
    DELINS
    Alleles:
    CTCTCTCTCTCTCTCTCTCTCTCTCT>-,CTCT,CTCTCT,CTCTCTCT,CTCTCTCTCT,CTCTCTCTCTCT,CTCTCTCTCTCTCT,CTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT [Show Flanks]
    Chromosome:
    21:35038589 (GRCh38)
    21:36410886 (GRCh37)
    Canonical SPDI:
    NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT,NC_000021.9:35038572:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT:CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
    Gene:
    RUNX1 (Varview), RUNX1-IT1 (Varview)
    Functional Consequence:
    non_coding_transcript_variant,genic_upstream_transcript_variant,intron_variant
    Validated:
    by frequency,by alfa,by cluster
    MAF:
    CTCTCTCTCTCTCTCTCTCT=0./0 (ALFA)
    HGVS:
    NC_000021.9:g.35038573CT[8], NC_000021.9:g.35038573CT[10], NC_000021.9:g.35038573CT[11], NC_000021.9:g.35038573CT[12], NC_000021.9:g.35038573CT[13], NC_000021.9:g.35038573CT[14], NC_000021.9:g.35038573CT[15], NC_000021.9:g.35038573CT[16], NC_000021.9:g.35038573CT[17], NC_000021.9:g.35038573CT[18], NC_000021.9:g.35038573CT[19], NC_000021.9:g.35038573CT[20], NC_000021.9:g.35038573CT[22], NC_000021.9:g.35038573CT[23], NC_000021.9:g.35038573CT[24], NC_000021.9:g.35038573CT[25], NC_000021.9:g.35038573CT[26], NC_000021.9:g.35038573CT[27], NC_000021.9:g.35038573CT[28], NC_000021.9:g.35038573CT[30], NC_000021.9:g.35038573CT[32], NC_000021.9:g.35038573CT[33], NC_000021.8:g.36410870CT[8], NC_000021.8:g.36410870CT[10], NC_000021.8:g.36410870CT[11], NC_000021.8:g.36410870CT[12], NC_000021.8:g.36410870CT[13], NC_000021.8:g.36410870CT[14], NC_000021.8:g.36410870CT[15], NC_000021.8:g.36410870CT[16], NC_000021.8:g.36410870CT[17], NC_000021.8:g.36410870CT[18], NC_000021.8:g.36410870CT[19], NC_000021.8:g.36410870CT[20], NC_000021.8:g.36410870CT[22], NC_000021.8:g.36410870CT[23], NC_000021.8:g.36410870CT[24], NC_000021.8:g.36410870CT[25], NC_000021.8:g.36410870CT[26], NC_000021.8:g.36410870CT[27], NC_000021.8:g.36410870CT[28], NC_000021.8:g.36410870CT[30], NC_000021.8:g.36410870CT[32], NC_000021.8:g.36410870CT[33], NG_011402.2:g.951098AG[8], NG_011402.2:g.951098AG[10], NG_011402.2:g.951098AG[11], NG_011402.2:g.951098AG[12], NG_011402.2:g.951098AG[13], NG_011402.2:g.951098AG[14], NG_011402.2:g.951098AG[15], NG_011402.2:g.951098AG[16], NG_011402.2:g.951098AG[17], NG_011402.2:g.951098AG[18], NG_011402.2:g.951098AG[19], NG_011402.2:g.951098AG[20], NG_011402.2:g.951098AG[22], NG_011402.2:g.951098AG[23], NG_011402.2:g.951098AG[24], NG_011402.2:g.951098AG[25], NG_011402.2:g.951098AG[26], NG_011402.2:g.951098AG[27], NG_011402.2:g.951098AG[28], NG_011402.2:g.951098AG[30], NG_011402.2:g.951098AG[32], NG_011402.2:g.951098AG[33], NR_026812.1:n.813AG[8], NR_026812.1:n.813AG[10], NR_026812.1:n.813AG[11], NR_026812.1:n.813AG[12], NR_026812.1:n.813AG[13], NR_026812.1:n.813AG[14], NR_026812.1:n.813AG[15], NR_026812.1:n.813AG[16], NR_026812.1:n.813AG[17], NR_026812.1:n.813AG[18], NR_026812.1:n.813AG[19], NR_026812.1:n.813AG[20], NR_026812.1:n.813AG[22], NR_026812.1:n.813AG[23], NR_026812.1:n.813AG[24], NR_026812.1:n.813AG[25], NR_026812.1:n.813AG[26], NR_026812.1:n.813AG[27], NR_026812.1:n.813AG[28], NR_026812.1:n.813AG[30], NR_026812.1:n.813AG[32], NR_026812.1:n.813AG[33], NM_025143.1:c.259_260dup, NM_025143.1:c.237_260del, NM_025143.1:c.241_260del, NM_025143.1:c.243_260del, NM_025143.1:c.245_260del, NM_025143.1:c.247_260del, NM_025143.1:c.249_260del, NM_025143.1:c.251_260del, NM_025143.1:c.253_260del, NM_025143.1:c.255_260del, NM_025143.1:c.257_260del, NM_025143.1:c.259_260del, NM_025143.1:c.257_260dup, NM_025143.1:c.255_260dup, NM_025143.1:c.253_260dup, NM_025143.1:c.251_260dup, NM_025143.1:c.249_260dup, NM_025143.1:c.247_260dup, NM_025143.1:c.245_260dup, NM_025143.1:c.241_260dup, NM_025143.1:c.237_260dup, NM_025143.1:c.235_260dup
    2.

    rs1491302185 [Homo sapiens]
      Variant type:
      DELINS
      Alleles:
      ->TA [Show Flanks]
      Chromosome:
      21:35038647 (GRCh38)
      21:36410945 (GRCh37)
      Canonical SPDI:
      NC_000021.9:35038647:A:ATA
      Gene:
      RUNX1 (Varview), RUNX1-IT1 (Varview)
      Functional Consequence:
      genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
      Validated:
      by frequency,by alfa,by cluster
      MAF:
      ATA=0./0 (ALFA)
      AT=0.000004/1 (TOPMED)
      AT=0.000051/7 (GnomAD)
      HGVS:
      3.

      rs1489530775 [Homo sapiens]
        Variant type:
        DEL
        Alleles:
        C>- [Show Flanks]
        Chromosome:
        21:35038597 (GRCh38)
        21:36410894 (GRCh37)
        Canonical SPDI:
        NC_000021.9:35038596:C:
        Gene:
        RUNX1 (Varview), RUNX1-IT1 (Varview)
        Functional Consequence:
        genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
        Validated:
        by cluster
        HGVS:
        4.

        rs1489319135 [Homo sapiens]
          Variant type:
          SNV
          Alleles:
          A>G [Show Flanks]
          Chromosome:
          21:35038244 (GRCh38)
          21:36410541 (GRCh37)
          Canonical SPDI:
          NC_000021.9:35038243:A:G
          Gene:
          RUNX1 (Varview), RUNX1-IT1 (Varview)
          Functional Consequence:
          genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
          Validated:
          by frequency,by alfa,by cluster
          MAF:
          G=0./0 (ALFA)
          G=0.000004/1 (TOPMED)
          G=0.000007/1 (GnomAD)
          HGVS:
          5.

          rs1488775520 [Homo sapiens]
            Variant type:
            SNV
            Alleles:
            C>G [Show Flanks]
            Chromosome:
            21:35038266 (GRCh38)
            21:36410563 (GRCh37)
            Canonical SPDI:
            NC_000021.9:35038265:C:G
            Gene:
            RUNX1 (Varview), RUNX1-IT1 (Varview)
            Functional Consequence:
            genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
            Validated:
            by frequency,by alfa,by cluster
            MAF:
            G=0./0 (ALFA)
            G=0.000004/1 (TOPMED)
            G=0.000014/2 (GnomAD)
            HGVS:
            6.

            rs1488285818 [Homo sapiens]
              Variant type:
              SNV
              Alleles:
              C>A [Show Flanks]
              Chromosome:
              21:35037432 (GRCh38)
              21:36409729 (GRCh37)
              Canonical SPDI:
              NC_000021.9:35037431:C:A
              Gene:
              RUNX1 (Varview), RUNX1-IT1 (Varview)
              Functional Consequence:
              genic_upstream_transcript_variant,downstream_transcript_variant,500B_downstream_variant,intron_variant
              Validated:
              by frequency,by alfa,by cluster
              MAF:
              A=0./0 (ALFA)
              A=0.000008/2 (TOPMED)
              A=0.000029/4 (GnomAD)
              HGVS:
              7.

              rs1488098797 [Homo sapiens]
                Variant type:
                SNV
                Alleles:
                A>G [Show Flanks]
                Chromosome:
                21:35038190 (GRCh38)
                21:36410487 (GRCh37)
                Canonical SPDI:
                NC_000021.9:35038189:A:G
                Gene:
                RUNX1 (Varview), RUNX1-IT1 (Varview)
                Functional Consequence:
                genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                Validated:
                by frequency,by alfa,by cluster
                MAF:
                G=0./0 (ALFA)
                G=0.000014/2 (GnomAD)
                G=0.000019/5 (TOPMED)
                HGVS:
                8.

                rs1487956522 [Homo sapiens]
                  Variant type:
                  DELINS
                  Alleles:
                  ->CCT [Show Flanks]
                  Chromosome:
                  21:35038612 (GRCh38)
                  21:36410910 (GRCh37)
                  Canonical SPDI:
                  NC_000021.9:35038612:CT:CTCCT
                  Gene:
                  RUNX1 (Varview), RUNX1-IT1 (Varview)
                  Functional Consequence:
                  genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                  HGVS:
                  9.

                  rs1487538892 [Homo sapiens]
                    Variant type:
                    DELINS
                    Alleles:
                    CTGT>- [Show Flanks]
                    Chromosome:
                    21:35038613 (GRCh38)
                    21:36410910 (GRCh37)
                    Canonical SPDI:
                    NC_000021.9:35038611:TCTGT:T
                    Gene:
                    RUNX1 (Varview), RUNX1-IT1 (Varview)
                    Functional Consequence:
                    genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                    Validated:
                    by frequency,by alfa,by cluster
                    MAF:
                    T=0.005901/70 (ALFA)
                    -=0.007772/795 (GnomAD)
                    -=0.016925/284 (TOMMO)
                    -=0.026667/16 (NorthernSweden)
                    HGVS:
                    10.

                    rs1486165739 [Homo sapiens]
                      Variant type:
                      SNV
                      Alleles:
                      T>G [Show Flanks]
                      Chromosome:
                      21:35039918 (GRCh38)
                      21:36412215 (GRCh37)
                      Canonical SPDI:
                      NC_000021.9:35039917:T:G
                      Gene:
                      RUNX1 (Varview), RUNX1-IT1 (Varview)
                      Functional Consequence:
                      upstream_transcript_variant,genic_upstream_transcript_variant,2KB_upstream_variant,intron_variant
                      Validated:
                      by frequency,by alfa,by cluster
                      MAF:
                      G=0./0 (ALFA)
                      G=0.000007/1 (GnomAD)
                      G=0.000011/3 (TOPMED)
                      HGVS:
                      11.

                      rs1485526125 [Homo sapiens]
                        Variant type:
                        SNV
                        Alleles:
                        G>A [Show Flanks]
                        Chromosome:
                        21:35038965 (GRCh38)
                        21:36411262 (GRCh37)
                        Canonical SPDI:
                        NC_000021.9:35038964:G:A
                        Gene:
                        RUNX1 (Varview), RUNX1-IT1 (Varview)
                        Functional Consequence:
                        genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                        Validated:
                        by frequency,by alfa,by cluster
                        MAF:
                        A=0./0 (ALFA)
                        A=0.000011/3 (TOPMED)
                        A=0.000014/2 (GnomAD)
                        HGVS:
                        12.

                        rs1485076916 [Homo sapiens]
                          Variant type:
                          SNV
                          Alleles:
                          C>G [Show Flanks]
                          Chromosome:
                          21:35038581 (GRCh38)
                          21:36410878 (GRCh37)
                          Canonical SPDI:
                          NC_000021.9:35038580:C:G
                          Gene:
                          RUNX1 (Varview), RUNX1-IT1 (Varview)
                          Functional Consequence:
                          genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                          Validated:
                          by frequency,by alfa
                          MAF:
                          G=0./0 (ALFA)
                          C=0.5/1 (SGDP_PRJ)
                          HGVS:
                          13.

                          rs1484542705 [Homo sapiens]
                            Variant type:
                            SNV
                            Alleles:
                            C>T [Show Flanks]
                            Chromosome:
                            21:35039418 (GRCh38)
                            21:36411715 (GRCh37)
                            Canonical SPDI:
                            NC_000021.9:35039417:C:T
                            Gene:
                            RUNX1 (Varview), RUNX1-IT1 (Varview)
                            Functional Consequence:
                            genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                            Validated:
                            by frequency,by alfa
                            MAF:
                            T=0./0 (ALFA)
                            T=0.000011/3 (TOPMED)
                            HGVS:
                            14.

                            rs1484487463 [Homo sapiens]
                              Variant type:
                              SNV
                              Alleles:
                              G>C [Show Flanks]
                              Chromosome:
                              21:35038437 (GRCh38)
                              21:36410734 (GRCh37)
                              Canonical SPDI:
                              NC_000021.9:35038436:G:C
                              Gene:
                              RUNX1 (Varview), RUNX1-IT1 (Varview)
                              Functional Consequence:
                              genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                              HGVS:
                              15.

                              rs1484202424 [Homo sapiens]
                                Variant type:
                                SNV
                                Alleles:
                                A>C [Show Flanks]
                                Chromosome:
                                21:35040789 (GRCh38)
                                21:36413086 (GRCh37)
                                Canonical SPDI:
                                NC_000021.9:35040788:A:C
                                Gene:
                                RUNX1 (Varview), RUNX1-IT1 (Varview)
                                Functional Consequence:
                                upstream_transcript_variant,genic_upstream_transcript_variant,2KB_upstream_variant,intron_variant
                                Validated:
                                by frequency,by alfa,by cluster
                                MAF:
                                C=0./0 (ALFA)
                                C=0.000004/1 (TOPMED)
                                C=0.000546/1 (Korea1K)
                                HGVS:
                                16.

                                rs1483923891 [Homo sapiens]
                                  Variant type:
                                  SNV
                                  Alleles:
                                  A>G [Show Flanks]
                                  Chromosome:
                                  21:35038552 (GRCh38)
                                  21:36410849 (GRCh37)
                                  Canonical SPDI:
                                  NC_000021.9:35038551:A:G
                                  Gene:
                                  RUNX1 (Varview), RUNX1-IT1 (Varview)
                                  Functional Consequence:
                                  genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                                  Validated:
                                  by frequency,by alfa
                                  MAF:
                                  G=0./0 (ALFA)
                                  HGVS:
                                  17.

                                  rs1483798873 [Homo sapiens]
                                    Variant type:
                                    SNV
                                    Alleles:
                                    T>A [Show Flanks]
                                    Chromosome:
                                    21:35040865 (GRCh38)
                                    21:36413162 (GRCh37)
                                    Canonical SPDI:
                                    NC_000021.9:35040864:T:A
                                    Gene:
                                    RUNX1 (Varview), RUNX1-IT1 (Varview)
                                    Functional Consequence:
                                    upstream_transcript_variant,genic_upstream_transcript_variant,2KB_upstream_variant,intron_variant
                                    Validated:
                                    by frequency,by alfa
                                    MAF:
                                    A=0./0 (ALFA)
                                    A=0.000004/1 (TOPMED)
                                    HGVS:
                                    18.

                                    rs1483043630 [Homo sapiens]
                                      Variant type:
                                      SNV
                                      Alleles:
                                      C>G [Show Flanks]
                                      Chromosome:
                                      21:35040974 (GRCh38)
                                      21:36413271 (GRCh37)
                                      Canonical SPDI:
                                      NC_000021.9:35040973:C:G
                                      Gene:
                                      RUNX1 (Varview), RUNX1-IT1 (Varview)
                                      Functional Consequence:
                                      upstream_transcript_variant,genic_upstream_transcript_variant,2KB_upstream_variant,intron_variant
                                      Validated:
                                      by frequency,by alfa,by cluster
                                      MAF:
                                      G=0./0 (ALFA)
                                      G=0.000004/1 (TOPMED)
                                      G=0.000007/1 (GnomAD)
                                      HGVS:
                                      19.

                                      rs1482792700 [Homo sapiens]
                                        Variant type:
                                        SNV
                                        Alleles:
                                        C>T [Show Flanks]
                                        Chromosome:
                                        21:35039401 (GRCh38)
                                        21:36411698 (GRCh37)
                                        Canonical SPDI:
                                        NC_000021.9:35039400:C:T
                                        Gene:
                                        RUNX1 (Varview), RUNX1-IT1 (Varview)
                                        Functional Consequence:
                                        genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                                        Validated:
                                        by frequency,by alfa,by cluster
                                        MAF:
                                        T=0./0 (ALFA)
                                        T=0.000008/2 (TOPMED)
                                        T=0.000014/2 (GnomAD)
                                        T=0.000035/1 (TOMMO)
                                        HGVS:
                                        20.

                                        rs1482679097 [Homo sapiens]
                                          Variant type:
                                          SNV
                                          Alleles:
                                          G>A [Show Flanks]
                                          Chromosome:
                                          21:35039279 (GRCh38)
                                          21:36411576 (GRCh37)
                                          Canonical SPDI:
                                          NC_000021.9:35039278:G:A
                                          Gene:
                                          RUNX1 (Varview), RUNX1-IT1 (Varview)
                                          Functional Consequence:
                                          genic_upstream_transcript_variant,non_coding_transcript_variant,intron_variant
                                          Validated:
                                          by frequency,by alfa,by cluster
                                          MAF:
                                          A=0./0 (ALFA)
                                          A=0.000004/1 (TOPMED)
                                          A=0.000007/1 (GnomAD)
                                          HGVS:

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