show Abstracthide AbstractEscherichia coli is a Gram-negative, rod shape, and facultative anaerobic. This bacteria is found in the intestinal tract of animals and human. E. coli strains causing enteric infections are mostly called diarrheagenic E. coli strains, and their pathogenesis is associated with a different number of virulence genes, which vary according to pathotype. Diarrheagenic Escherichia coli are classified into 6 serotypes, Enteropathogenic E. coli (EPEC), enterotoxigenic E. coli (ETEC), enteroinvasive E. coli (EIEC), enteroaggregative E. coli (EAEC), diffusely adherent E. coli (DAEC) and Shiga toxin-producing E. coli (STEC).Shiga toxin–producing Escherichia coli (STEC) are the most important foodborne pathogens, causing human disease. STEC O157:H7 is classified as the most important serotype in relation to human infection, non-O157 cases are also increasingly reported. Most STEC recognized to the well-defined top-5 (O157, O26, O103, and O145). STEC is transmitted from host to host by the fecal-oral route over contaminated surfaces, food, waters and human. Usually infected children and adults by these bacteria out of human contact, are the most probable. The whole-genome sequencing data of STEC will be useful to compare genomic sequences in clinical, food and environmental samples STEC isolates.