show Abstracthide AbstractThe emergence and persistence of extended-spectrum cephalosporin resistance (ESC-R) is a major public health problem worldwide. This study aimed to generate long-read data for 20 ESC-R E. coli genomes, which are part of a large collection with short-read data (PRJEB50837 and PRJNA523640 [SAMN10985367]). This long-read data were used to confirm the localization of the ESC-R genes in plasmids or in the chromosome. All 20 genomes were sequenced using the MinION sequencing device (Oxford Nanopore Technologies). Note: raw reads were submitted for almost all genomes except for one genome (SAMEA110398701), where a filtered reads file was submitted.