RNA-seq THP-1cells infected with wt PG for 2 h - SRA

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SRX22424169: RNA-seq THP-1cells infected with wt PG for 2 h
1 ILLUMINA (Illumina NovaSeq 6000) run: 41.8M spots, 12.6G bases, 4Gb downloads

Design: RNA extracted from THP-1 cell infected with porphyromonas gingivalis

Submitted by: University of Florida

Study: A Porphyromonas gingivalis hypothetical protein controlled by the type I-C CRISPR-Cas system is a novel adhesin important in virulence.

PRJNA1037128 • SRP470815 • All experiments • All runs

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The present study demonstrates that the hypothetical protein PGN_1547 form Porphyromonas gingivalis acts as an essential virulence factor, as shown in a Galleria mellonella model for virulence. Moreover, we demonstrated that PGN_1547 is an adhesin essential in adhesion to THP-1 cells. We propose that PGN_1547 may be an essential virulence factor in P. gingivalis.

Sample: collected after 2 hs

SAMN38163863 • SRS19455798 • All experiments • All runs

Organism: Porphyromonas gingivalis ATCC 33277

Library:

Name: WT2

Instrument: Illumina NovaSeq 6000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: RT-PCR

Layout: PAIRED

Runs: 1 run, 41.8M spots, 12.6G bases, 4Gb

Run	# of Spots	# of Bases	Size	Published
SRR26725269	41,755,094	12.6G	4Gb	2024-01-08

ID:: 30409601

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