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SRX26752059: RNA-Seq of Mus musculus vaccine specific splenic Notch 1/2 KO CD8 T cells
1 ILLUMINA (Illumina NovaSeq X) run: 47.6M spots, 13.2G bases, 4.4Gb downloads

Design: Notch 1/2 KO (Notch1 fl/fl; Notch2 fl/fl; CD4-CRE) and WT (Notch1 fl/fl; Notch2 fl/fl) mice were vaccinated epidermally at day 0, 3 and 6 with DNA vaccine encoding HPV E7 protein. At day 10, mice were euthanized to collect spleens, vaccine specific CD8 T cells were FACS sorted using tetramers. Each sample contains pooled splenocytes from 3 distinct animals.
Submitted by: Sanquin research
Study: Notch 1/2 KO CD8 T cells transcriptome
show Abstracthide Abstract
Transcriptome from murine CD8 T cell elicited 10 days post vaccination with an E7 DNA vaccine on Notch 1/2 KO (Notch1 fl/fl; Notch2 fl/fl; CD4-CRE) vs WT mice (Notch1 fl/fl; Notch2 fl/fl). The aim of the study is to characterize the contribution of Notch signaling during the priming of CD8 T cells.
Sample:
SAMN44793885 • SRS23240672 • All experiments • All runs
Organism: Mus musculus
Library:
Name: KO1
Instrument: Illumina NovaSeq X
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: PolyA
Layout: PAIRED
Runs: 1 run, 47.6M spots, 13.2G bases, 4.4Gb
Run# of Spots# of BasesSizePublished
SRR3137852847,641,56913.2G4.4Gb2024-11-18

ID:
36155132

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