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SRX27160648: WGS of micobacterium tuberculosis
1 DNBSEQ (DNBSEQ-G400) run: 1.2M spots, 356.4M bases, 163.1Mb downloads

Design: NBE flex DNA library prep
Submitted by: Armauer Hansen Research Institute
Study: Comparative growth kinetics and drug susceptibility of Mycobacterium 2 tuberculosis lineages prevalent in Ethiopia: Implications for tuberculosis 3 treatment and management
show Abstracthide Abstract
Mtb strains, including sub-lineages 4.1.2.1, 4.2.2.2, 4.6.3, lineages 3 and 7, and the reference strain H37Rv (ATCC 27294), were cultured in liquid 7H9 Middlebrook broth. Growth began on day 6 post-inoculation. Sub-lineage 4.1.2.1 showed rapid exponential growth by day 9, reaching the stationary phase by day 15. Sub-lineage 4.1.2.1 followed by sub-lineage 4.2.2.2 had the highest maximum growth concentration (Cmax), indicating enhanced growth efficiency and adaptive traits that may increase their pathogenicity or resistance to host defenses or anti-TB drugs.
Sample: MtbEth5
SAMN45934041 • SRS23614722 • All experiments • All runs
Library:
Name: MtbEth_012
Instrument: DNBSEQ-G400
Strategy: WGS
Source: GENOMIC
Selection: PCR
Layout: PAIRED
Runs: 1 run, 1.2M spots, 356.4M bases, 163.1Mb
Run# of Spots# of BasesSizePublished
SRR317998141,211,006356.4M163.1Mb2024-12-21

ID:
36648158

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