4A55: Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108

PDB ID: 4A55Download
MMDB ID: 96185
PDB Deposition Date: 2011/10/24
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 4A55: dimeric; determined by author and by software (PISA)
Molecular Components in 4A55
Label Count Molecule
Proteins (2 molecules)
1
Phosphatidylinositol-4,5-bisphosphate 3-kinase Catalytic Subunit Alpha Isoform
Molecule annotation
1
Phosphatidylinositol 3-kinase Regulatory Subunit Alpha
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
PIK-108PIK-108
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303