4K5Y: Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395

PDB ID: 4K5YDownload
MMDB ID: 111862
PDB Deposition Date: 2013/4/15
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.977  Å
Source Organism:
Similar Structures:
Biological Unit for 4K5Y: monomeric; determined by author
Molecular Components in 4K5Y
Label Count Molecule
Protein (1 molecule)
1
Corticotropin-releasing Factor Receptor 1, T4-lysozyme Chimeric Construct
(Gene symbol: e)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine
2
1
OLEIC ACIDOLEIC ACID
3
3
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
4
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303