7W72: Structure of a human glycosylphosphatidylinositol (GPI) transamidase

PDB ID: 7W72Download
MMDB ID: 212051
PDB Deposition Date: 2021/12/2
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 7W72: pentameric; determined by author
Molecular Components in 7W72
Label Count Molecule
Proteins (5 molecules)
1
Phosphatidylinositol Glycan Anchor Biosynthesis Class U Protein
(Gene symbol: PIGU)
Molecule annotation
1
GPI Transamidase Component Pig-s
(Gene symbol: PIGS)
Molecule annotation
1
GPI Transamidase Component Pig-t
(Gene symbol: PIGT)
Molecule annotation
1
Gpi-anchor Transamidase
(Gene symbol: PIGK)
Molecule annotation
1
Glycosylphosphatidylinositol Anchor Attachment 1 Protein
(Gene symbol: GPAA1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose (Link to PubChem not yet available)2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranose (Link to PubChem not yet available)beta-D-mannopyranose
3
1
[2-[[(2~{R})-2-hexanoyloxy-3-[(~{E})-hex-3-enoxy]propoxy]-oxidanyl-phosphoryl]oxy-3,4,5,6-tetrakis(oxidanyl)phenyl] (2~{E},4~{E})-hepta-2,4-dienoate (Link to PubChem not yet available)[2-[[(2~{R})-2-hexanoyloxy-3-[(~{E})-hex-3-enoxy]propoxy]-oxidanyl-phosphoryl]oxy-3,4,5,6-tetrakis(oxidanyl)phenyl] (2~{E},4~{E})-hepta-2,4-dienoate
4
1
CALCIUM ION (Link to PubChem not yet available)CALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303