7LW1: Human phosphofructokinase-1 liver type bound to activator NA-11

PDB ID: 7LW1Download
MMDB ID: 211110
PDB Deposition Date: 2021/2/27
Updated in MMDB: 2024/06
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7LW1: tetrameric; determined by author
Molecular Components in 7LW1
Label Count Molecule
Proteins (4 molecules)
4
Atp-dependent 6-phosphofructokinase, Liver Type
(Gene symbol: PFKL)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
N-{(11S)-2-[2-(5-hydroxypent-1-yn-1-yl)phenyl]-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl}acetamideN-{(11S)-2-[2-(5-hydroxypent-1-yn-1-yl)phenyl]-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl}acetamide
2
4
1,6-di-O-phosphono-beta-D-fructofuranose1,6-di-O-phosphono-beta-D-fructofuranose
3
4
6-O-phosphono-beta-D-fructofuranose6-O-phosphono-beta-D-fructofuranose
4
4
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303