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8WQG:
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
PDB ID:
8WQG
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MMDB ID:
245044
PDB Deposition Date:
2023/10/11
Updated in MMDB:
2024/10
Experimental Method:
electron microscopy
Resolution:
4.09 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 8WQG: dodecameric; determined by author
Molecular Components in 8WQG
Label
Count
Molecule
Proteins (12 molecules)
D
I
2
Elongin-b
(Gene symbol:
ELOB
)
F
J
2
E3 Ubiquitin-protein Ligase Rbx1, N-terminally Processed
(Gene symbol:
RBX1
)
B
H
2
Elongin-c
(Gene symbol:
ELOC
)
C
E
2
Cullin-2
(Gene symbol:
CUL2
)
N
K
2
Nedd8
(Gene symbol:
NEDD8
)
A
G
2
Protein Fem-1 Homolog B
(Gene symbol:
FEM1B
)
Chemicals and Non-standard biopolymers (6 molecules)
1
6
ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303