5FA5: Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide

PDB ID: 5FA5Download
MMDB ID: 136785
PDB Deposition Date: 2015/12/10
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.34  Å
Source Organism:
Similar Structures:
Biological Unit for 5FA5: dodecameric; determined by software (PISA)
Molecular Components in 5FA5
Label Count Molecule
Proteins (12 molecules)
4
Protein Arginine N-methyltransferase 5
(Gene symbol: PRMT5)
Molecule annotation
4
Methylosome Protein 50
(Gene symbol: WDR77)
Molecule annotation
4
Histone H4
(Gene symbol: H4C9)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
5'-DEOXY-5'-METHYLTHIOADENOSINE5'-DEOXY-5'-METHYLTHIOADENOSINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303