2F9U: HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with a P2 norborane

PDB ID: 2F9UDownload
MMDB ID: 39248
PDB Deposition Date: 2005/12/6
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Hepacivirus hominis▼
Similar Structures:
Biological Unit for 2F9U: tetrameric; determined by author and by software (PISA)
Molecular Components in 2F9U
Label Count Molecule
Proteins (4 molecules)
2
NS3 Protease/helicase'
Molecule annotation
2
Polyprotein
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
ZINC IONZINC ION
2
1
1,1-DIMETHYLETHYL [1-CYCLOHEXYL-2-[3-[[[1-[2-[[2-[[2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO]-2-OXOETHYL]AMINO]-1,2-DIOXOETHYL]PENTYL]AMINO]CARBONYL]-2-AZABICYCLO[2.2.1]HEPTAN-2-YL]-2-OXOETHYL]CARBAMATE1,1-DIMETHYLETHYL [1-CYCLOHEXYL-2-[3-[[[1-[2-[[2-[[2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO]-2-OXOETHYL]AMINO]-1,2-DIOXOETHYL]PENTYL]AMINO]CARBONYL]-2-AZABICYCLO[2.2.1]HEPTAN-2-YL]-2-OXOETHYL]CARBAMATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303