5US1: Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A

PDB ID: 5US1Download
MMDB ID: 148453
PDB Deposition Date: 2017/2/13
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.48  Å
Source Organism:
Similar Structures:
Biological Unit for 5US1: dimeric; determined by author and by software (PISA)
Molecular Components in 5US1
Label Count Molecule
Proteins (2 molecules)
2
Aminoglycoside 2'-n-acetyltransferase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside(1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside
2
1
D(-)-TARTARIC ACIDD(-)-TARTARIC ACID
3
1
COENZYME ACOENZYME A
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303