6C24: Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State

PDB ID: 6C24Download
MMDB ID: 158598
PDB Deposition Date: 2018/1/6
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Molecular Components in 6C24
Label Count Molecule
Proteins (12 molecules)
3
Polycomb Protein Suz12
(Gene symbol: SUZ12)
Molecule annotation
1
Protein Jumonji
(Gene symbol: JARID2)
Molecule annotation
1
Protein Jumonji
(Gene symbol: JARID2)
Molecule annotation
2
Histone-lysine N-methyltransferase Ezh2
(Gene symbol: EZH2)
Molecule annotation
1
Polycomb Protein EED
(Gene symbol: EED)
Molecule annotation
1
Histone-binding Protein Rbbp4
(Gene symbol: RBBP4)
Molecule annotation
1
Jarid2-substrate
Molecule annotation
1
Zinc Finger Protein Aebp2
(Gene symbol: AEBP2)
Molecule annotation
1
Suz12
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303