2OIP: Crystal Structure of the S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis

PDB ID: 2OIPDownload
MMDB ID: 47454
PDB Deposition Date: 2007/1/11
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2OIP: dimeric; determined by author and by software (PISA)
Molecular Components in 2OIP
Label Count Molecule
Proteins (2 molecules)
2
Chain A, Crystal Structure of Dhfr
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
3
2
METHOTREXATEMETHOTREXATE
4
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303