7UX2: cryo-EM structure of the Raptor-TFEB-Rag-Ragulator complex

PDB ID: 7UX2Download
MMDB ID: 223784
PDB Deposition Date: 2022/5/4
Updated in MMDB: 2022/12
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7UX2: hexadecameric; determined by author
Molecular Components in 7UX2
Label Count Molecule
Proteins (16 molecules)
1
Regulatory-associated Protein of Mtor
(Gene symbol: RPTOR)
Molecule annotation
2
Ras-related Gtp-binding Protein a
(Gene symbol: RRAGA)
Molecule annotation
2
Ras-related Gtp-binding Protein C
(Gene symbol: RRAGC)
Molecule annotation
2
Ragulator Complex Protein Lamtor1
(Gene symbol: LAMTOR1)
Molecule annotation
2
Ragulator Complex Protein Lamtor2
(Gene symbol: LAMTOR2)
Molecule annotation
2
Ragulator Complex Protein Lamtor3
(Gene symbol: LAMTOR3)
Molecule annotation
2
Ragulator Complex Protein Lamtor4
(Gene symbol: LAMTOR4)
Molecule annotation
2
Ragulator Complex Protein Lamtor5
(Gene symbol: LAMTOR5)
Molecule annotation
1
Transcription Factor EB
(Gene symbol: TFEB)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303