National Center for
Biotechnology Information

8CRX: Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound

PDB ID:

8CRX Download

MMDB ID:

228084

PDB Deposition Date:

2022/5/12

Updated in MMDB:

2024/10

Experimental Method:

electron microscopy

Resolution:

2.78 Å

Source Organism:

Cutibacterium acnes▼

Taxonomy	Molecule
Cutibacterium acnes	A, D, E, F, H, K, L, O, Q, R, T, P, X, G, I, J, M, N, S, U, B, c, d, e, f, g, i, j, k, l, m, n, o, p , q, r, s, t, u, v, w, x, y, z, 0, 1, 2, 4, a, b, V, 3
Escherichia coli	Y, C

Similar Structures:

Biological Unit for 8CRX: 54-meric; determined by author

Molecular Components in 8CRX
Label	Count	Molecule
Proteins (49 molecules)
D	1	30S Ribosomal Protein S4
E	1	30S Ribosomal Protein S5
F	1	30S Ribosomal Protein S6
H	1	30S Ribosomal Protein S8
K	1	30S Ribosomal Protein S11
L	1	30S Ribosomal Protein S12
O	1	30S Ribosomal Protein S15
Q	1	30S Ribosomal Protein S17
R	1	30S Ribosomal Protein S18
T	1	30S Ribosomal Protein S20
P	1	30S Ribosomal Protein S16
X	1	30S Ribosomal Protein Bs22
G	1	30S Ribosomal Protein S3
I	1	30S Ribosomal Protein S7
J	1	30S Ribosomal Protein S9
M	1	30S Ribosomal Protein S10
N	1	30S Ribosomal Protein S13
S	1	30S Ribosomal Protein S14 Type Z
U	1	30S Ribosomal Protein S19
B	1	30S Ribosomal Protein S2
c	1	50S Ribosomal Protein L2
d	1	50S Ribosomal Protein L3
e	1	50S Ribosomal Protein L4
f	1	50S Ribosomal Protein L5
g	1	50S Ribosomal Protein L6
i	1	50S Ribosomal Protein L13
j	1	50S Ribosomal Protein L14
k	1	50S Ribosomal Protein L15
l	1	50S Ribosomal Protein L16
m	1	50S Ribosomal Protein L17
n	1	50S Ribosomal Protein L18
o	1	50S Ribosomal Protein L19
p	1	50S Ribosomal Protein L20
q	1	50S Ribosomal Protein L21
r	1	50S Ribosomal Protein L22
s	1	50S Ribosomal Protein L23
t	1	50S Ribosomal Protein L24
u	1	50S Ribosomal Protein L25
v	1	50S Ribosomal Protein L27
w	1	50S Ribosomal Protein L28
x	1	50S Ribosomal Protein L29
y	1	50S Ribosomal Protein L30
z	1	50S Ribosomal Protein L32
0	1	50S Ribosomal Protein L33
1	1	50S Ribosomal Protein L34
2	1	50S Ribosomal Protein L35
4	1	50S Ribosomal Protein L31
V	1	50S Ribosomal Protein Bl37
3	1	50S Ribosomal Protein L36
Nucleotides(5 molecules)
A	1	RNA (1537-mer)
a	1	23S Ribosomal RNA
b	1	5S Ribosomal RNA
Y	1	32mf mRNA
C	1	P-site Initiator tRNA
Chemicals and Non-standard biopolymers (393 molecules)
1	2	Sarecycline
2	386	MAGNESIUM ION
3	5	ZINC ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303