8UD9: Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304

PDB ID: 8UD9Download
MMDB ID: 240303
PDB Deposition Date: 2023/9/28
Updated in MMDB: 2023/12
Experimental Method:
electron microscopy
Resolution: 2.04  Å
Source Organism:
Similar Structures:
Biological Unit for 8UD9: 28-meric; determined by author
Molecular Components in 8UD9
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Subunit Alpha Type-6
Molecule annotation
2
Proteasome Subunit Alpha Type-2
Molecule annotation
2
Proteasome Subunit Alpha Type-4
Molecule annotation
2
Proteasome Subunit Alpha Type-7
Molecule annotation
2
Proteasome Subunit Alpha Type-5
Molecule annotation
2
Proteasome Subunit Alpha Type-1
Molecule annotation
2
Proteasome Subunit Alpha Type-3
Molecule annotation
2
Proteasome Subunit Beta Type-6
Molecule annotation
2
Proteasome Subunit Beta Type-7
Molecule annotation
2
Proteasome Subunit Beta Type-3
Molecule annotation
2
Proteasome Subunit Beta Type-2
Molecule annotation
2
Proteasome Subunit Beta Type-5
Molecule annotation
2
Proteasome Subunit Beta Type-1
Molecule annotation
2
Proteasome Subunit Beta Type-4
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide(7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303