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Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine[PHOSPHOINOSITIDE 3-KINASE GAMMA]
View in iCn3D Similar StructuresPubMedProteinsConserved DomainsPubChem Compound
Structure of Pi3K gamma with inhibitor[TRANSFERASE]
Rational Design of PI3K-alpha Inhibitors that Exhibit Selectivity Over the PI3K-beta Isoform[TRANSFERASE/TRANSFERASE INHIBITOR]
View in iCn3D Similar StructuresProteinsConserved DomainsPubChem Compound
Discovery of GDC-0980: a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor for the Treatment of Cancer[TRANSFER...
Fragment based discovery of a novel and selective PI3 Kinase inhibitor[TRANSFERASE]
Fragment Bound to PI3Kinase gamma[TRANSFERASE]
Structure-based design of thienobenzoxepin inhibitors of PI3-Kinase[TRANSFERASE/TRANSFERASE INHIBITOR]
Structure-based design of thienobenzoxepin inhibitors of PI3- kinase[TRANSFERASE/TRANSFERASE INHIBITOR]
Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors[TRANSFERASE/TRANSFERASE INHIBITOR]
4-Methylpteridineones as Orally Active and Selective PI3K/mTOR Dual Inhibitors[TRANSFERASE/TRANSFERASE INHIBITOR]
Structure of Pi3K gamma with a potent inhibitor: GSK2126458[TRANSFERASE]
Discovery of (thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer[TRANSFERASE]
Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors[TRANSFERASE]
Structure of PI3K gamma in complex with GDC0941[TRANSFERASE]
Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor DW2[TRANSFERASE]
Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor E5E2[TRANSFERASE]
Crystal structure of human PI3K-gamma in complex with CH5039699[Transferase/Transferase inhibitor]
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