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Efcab3 EF-hand calcium binding domain 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303589, updated on 4-Jan-2025

Summary

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Symbol
Efcab3provided by RGD
Full Name
EF-hand calcium binding domain 3provided by RGD
Primary source
RGD:1305423
See related
EnsemblRapid:ENSRNOG00000042255 AllianceGenome:RGD:1305423
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305423
Summary
Predicted to enable calcium ion binding activity. Orthologous to human EFCAB3 (EF-hand calcium binding domain 3). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Restricted expression toward (RPKM 169.9) See more
Orthologs
human mouse all
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Genomic context

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See Efcab3 in Genome Data Viewer
Location:
10q32.1
Exon count:
190
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (90084495..90577145)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (89583526..90077260)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (93304559..93332849)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase pi 1, pseudogene 2 Neighboring gene uncharacterized LOC134480888 Neighboring gene integrin subunit beta 3 Neighboring gene uncharacterized LOC108352141 Neighboring gene U6 spliceosomal RNA Neighboring gene methyltransferase like 2 Neighboring gene cactin, spliceosome C complex subunit, pseudogene 2 Neighboring gene tousled-like kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC156757

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
EF-hand calcium-binding domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013972.3 → NP_001013994.1  EF-hand calcium-binding domain-containing protein 3

    See identical proteins and their annotated locations for NP_001013994.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    A0JPN9, Q66HC0
    UniProtKB/TrEMBL
    A6HJX2, F1LN12
    Related
    ENSRNOP00000008019.6, ENSRNOT00000008019.8
    Conserved Domains (2) summary
    pfam13499
    Location:51 → 108
    EF-hand_7; EF-hand domain pair
    pfam13833
    Location:62 → 113
    EF-hand_8; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    90084495..90577145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086129.2 → XP_038942057.1  EF-hand calcium-binding domain-containing protein 3 isoform X7

    Conserved Domains (2) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  2. XM_039086123.2 → XP_038942051.1  EF-hand calcium-binding domain-containing protein 3 isoform X1

    Related
    ENSRNOP00000104824.1, ENSRNOT00000150247.1
    Conserved Domains (3) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:6556 → 6606
    EF-hand_8; EF-hand domain pair

  3. XM_039086125.2 → XP_038942053.1  EF-hand calcium-binding domain-containing protein 3 isoform X3

    Conserved Domains (3) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:6538 → 6588
    EF-hand_8; EF-hand domain pair

  4. XM_039086126.2 → XP_038942054.1  EF-hand calcium-binding domain-containing protein 3 isoform X4

    Conserved Domains (3) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:6538 → 6588
    EF-hand_8; EF-hand domain pair

  5. XM_039086127.2 → XP_038942055.1  EF-hand calcium-binding domain-containing protein 3 isoform X5

    Conserved Domains (5) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    cd15897
    Location:4649 → 4673
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:4621 → 4743
    EFh_PEF; The penta-EF hand (PEF) family
    pfam13833
    Location:6521 → 6571
    EF-hand_8; EF-hand domain pair

  6. XM_039086128.2 → XP_038942056.1  EF-hand calcium-binding domain-containing protein 3 isoform X6

    Conserved Domains (3) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:6503 → 6553
    EF-hand_8; EF-hand domain pair

  7. XM_039086124.2 → XP_038942052.1  EF-hand calcium-binding domain-containing protein 3 isoform X2

    Conserved Domains (3) summary
    PTZ00184
    Location:155 → 286
    PTZ00184; calmodulin; Provisional
    COG5126
    Location:2598 → 2727
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:6555 → 6605
    EF-hand_8; EF-hand domain pair

  8. XM_039086130.2 → XP_038942058.1  EF-hand calcium-binding domain-containing protein 3 isoform X8

    Conserved Domains (2) summary
    COG5126
    Location:604 → 733
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:4562 → 4612
    EF-hand_8; EF-hand domain pair

  9. XM_039086131.1 → XP_038942059.1  EF-hand calcium-binding domain-containing protein 3 isoform X9

    Conserved Domains (2) summary
    COG5126
    Location:1653 → 1752
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:3638 → 3688
    EF-hand_8; EF-hand domain pair

  10. XM_039086132.1 → XP_038942060.1  EF-hand calcium-binding domain-containing protein 3 isoform X10

    Conserved Domains (2) summary
    COG5126
    Location:1486 → 1585
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    pfam13833
    Location:3471 → 3521
    EF-hand_8; EF-hand domain pair

  11. XM_063269182.1 → XP_063125252.1  EF-hand calcium-binding domain-containing protein 3 isoform X11

  12. XM_063269183.1 → XP_063125253.1  EF-hand calcium-binding domain-containing protein 3 isoform X12

    UniProtKB/Swiss-Prot
    A0JPN9, Q66HC0
    UniProtKB/TrEMBL
    A6HJX2, F1LN12
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q66HC0.1 GenPept UniProtKB/Swiss-Prot:Q66HC0

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