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    Zfp758 zinc finger protein 758 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690559, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Zfp758provided by RGD
    Official Full Name
    zinc finger protein 758provided by RGD
    Primary source
    RGD:1594701
    See related
    EnsemblRapid:ENSRNOG00000051867 AllianceGenome:RGD:1594701
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Zfp28
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 71.4), Lung (RPKM 68.2) and 9 other tissues See more
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    Genomic context

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    See Zfp758 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (70614167..70662261, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (61941284..61989354, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (38727137..38773604)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 845 like, pseudogene 1 Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene vomeronasal 2 receptor, 12 Neighboring gene vomeronasal 2 receptor, pseudogene 25

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 260-like
    Names
    zinc finger protein 28

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      70614167..70662261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277058.1 → XP_063133128.1  zinc finger protein 260-like

      UniProtKB/TrEMBL
      A0A0G2JV23

    2. XM_006228088.5 → XP_006228150.1  zinc finger protein 260-like

      See identical proteins and their annotated locations for XP_006228150.1

      UniProtKB/TrEMBL
      A0A0G2JV23
      Related
      ENSRNOP00000069321.1, ENSRNOT00000081537.3
      Conserved Domains (5) summary
      smart00349
      Location:13 → 55
      KRAB; krueppel associated box
      COG5048
      Location:209 → 634
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:269 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:253 → 278
      zf-H2C2_2; Zinc-finger double domain

    3. XM_063277062.1 → XP_063133132.1  zinc finger protein 260-like

      UniProtKB/TrEMBL
      A0A0G2JV23
    Nucleotide Protein Strain
    Heading Accession and Version

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