U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Slc43a3 solute carrier family 43, member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311170, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc43a3provided by RGD
    Official Full Name
    solute carrier family 43, member 3provided by RGD
    Primary source
    RGD:1312016
    See related
    EnsemblRapid:ENSRNOG00000061768 AllianceGenome:RGD:1312016
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable fatty acid transmembrane transporter activity; purine nucleobase transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Predicted to be involved in hypoxanthine transport. Predicted to be located in basolateral plasma membrane. Orthologous to human SLC43A3 (solute carrier family 43 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 136.7), Heart (RPKM 113.7) and 8 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slc43a3 in Genome Data Viewer
    Location:
    3q24
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (90414822..90450654)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (70008160..70030324)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (72328912..72351039)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 43 member 1 Neighboring gene uncharacterized LOC102554396 Neighboring gene reticulon 4 receptor-like 2 Neighboring gene solute carrier family 25 member 39, pseudogene 1 Neighboring gene proteoglycan 2, pro eosinophil major basic protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables adenine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables fatty acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables guanine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables xenobiotic transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in adenine transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in guanine transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hypoxanthine transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in xenobiotic transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    equilibrative nucleobase transporter 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107743.1NP_001101213.1  equilibrative nucleobase transporter 1

      See identical proteins and their annotated locations for NP_001101213.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473949
      UniProtKB/TrEMBL
      A0A8I6G8S9, A6HMS4
      Related
      ENSRNOP00000071799.1, ENSRNOT00000090256.3
      Conserved Domains (1) summary
      TIGR00893
      Location:61191
      2A0114; D-galactonate transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      90414822..90450654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234468.5XP_006234530.2  equilibrative nucleobase transporter 1 isoform X1

      See identical proteins and their annotated locations for XP_006234530.2

      UniProtKB/TrEMBL
      A0A8I6G8S9, D4A832
      Conserved Domains (1) summary
      TIGR00893
      Location:61191
      2A0114; D-galactonate transporter
    2. XM_063283653.1XP_063139723.1  equilibrative nucleobase transporter 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6G8S9
    3. XM_039104886.1XP_038960814.1  equilibrative nucleobase transporter 1 isoform X4

      Conserved Domains (1) summary
      cl28910
      Location:70172
      MFS; Major Facilitator Superfamily
    4. XM_006234470.5XP_006234532.1  equilibrative nucleobase transporter 1 isoform X1

      See identical proteins and their annotated locations for XP_006234532.1

      UniProtKB/TrEMBL
      A0A8I6G8S9, D4A832
      Conserved Domains (1) summary
      TIGR00893
      Location:61191
      2A0114; D-galactonate transporter
    5. XM_017591713.3XP_017447202.1  equilibrative nucleobase transporter 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZXF0, A0A8I6G8S9
      Related
      ENSRNOP00000084517.1, ENSRNOT00000115037.2
    6. XM_008761991.4XP_008760213.1  equilibrative nucleobase transporter 1 isoform X1

      See identical proteins and their annotated locations for XP_008760213.1

      UniProtKB/TrEMBL
      A0A8I6G8S9, D4A832
      Related
      ENSRNOP00000104917.1, ENSRNOT00000148051.1
      Conserved Domains (1) summary
      TIGR00893
      Location:61191
      2A0114; D-galactonate transporter
    7. XM_006234467.2XP_006234529.2  equilibrative nucleobase transporter 1 isoform X1

      See identical proteins and their annotated locations for XP_006234529.2

      UniProtKB/TrEMBL
      A0A8I6G8S9, D4A832
      Related
      ENSRNOP00000083320.1, ENSRNOT00000113415.2
      Conserved Domains (1) summary
      TIGR00893
      Location:61191
      2A0114; D-galactonate transporter
    8. XM_039104888.1XP_038960816.1  equilibrative nucleobase transporter 1 isoform X5