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    Cfap100 cilia and flagella associated protein 100 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297444, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cfap100provided by RGD
    Official Full Name
    cilia and flagella associated protein 100provided by RGD
    Primary source
    RGD:1305768
    See related
    EnsemblRapid:ENSRNOG00000017959 AllianceGenome:RGD:1305768
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc37; RGD1305768
    Summary
    Predicted to be active in ciliary basal body. Orthologous to human CFAP100 (cilia and flagella associated protein 100). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 56.3), Lung (RPKM 48.3) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cfap100 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (124471913..124495990, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (122914693..122938994, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (122314462..122338862, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene urocanate hydratase 1 Neighboring gene uncharacterized LOC134486812 Neighboring gene ZXD family zinc finger C Neighboring gene KLF transcription factor 15 Neighboring gene uncharacterized LOC134486813

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 37; cilia- and flagella-associated protein 100
    Names
    coiled-coil domain containing 37

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431711.1 → NP_001418640.1  coiled-coil domain-containing protein 37 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      D3ZEI2

    2. NM_001431712.1 → NP_001418641.1  coiled-coil domain-containing protein 37 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      D3ZEI2

    3. NM_001431713.1 → NP_001418642.1  coiled-coil domain-containing protein 37 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      D3ZEI2

    4. NM_001431714.1 → NP_001418643.1  coiled-coil domain-containing protein 37 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    5. NM_001431715.1 → NP_001418644.1  coiled-coil domain-containing protein 37 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RNA

    1. NR_197242.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    2. NR_197243.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      124471913..124495990 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108742.2 → XP_038964670.1  cilia- and flagella-associated protein 100 isoform X3

      Conserved Domains (1) summary
      pfam13863
      Location:126 → 244
      DUF4200; Domain of unknown function (DUF4200)

    2. XM_039108740.2 → XP_038964668.1  cilia- and flagella-associated protein 100 isoform X1

      Conserved Domains (1) summary
      pfam13863
      Location:152 → 270
      DUF4200; Domain of unknown function (DUF4200)

    3. XM_017593020.3 → XP_017448509.2  cilia- and flagella-associated protein 100 isoform X2

      Conserved Domains (1) summary
      pfam13863
      Location:130 → 248
      DUF4200; Domain of unknown function (DUF4200)

    4. XM_039108741.2 → XP_038964669.1  cilia- and flagella-associated protein 100 isoform X3

      Conserved Domains (1) summary
      pfam13863
      Location:126 → 244
      DUF4200; Domain of unknown function (DUF4200)

    5. XM_039108745.2 → XP_038964673.1  cilia- and flagella-associated protein 100 isoform X6

      Conserved Domains (2) summary
      TIGR02169
      Location:123 → 443
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam13863
      Location:152 → 270
      DUF4200; Domain of unknown function (DUF4200)

    6. XM_006236886.5 → XP_006236948.2  cilia- and flagella-associated protein 100 isoform X1

      Related
      ENSRNOP00000024222.8, ENSRNOT00000024222.9
      Conserved Domains (1) summary
      pfam13863
      Location:152 → 270
      DUF4200; Domain of unknown function (DUF4200)

    7. XM_006236885.5 → XP_006236947.2  cilia- and flagella-associated protein 100 isoform X1

      Conserved Domains (1) summary
      pfam13863
      Location:152 → 270
      DUF4200; Domain of unknown function (DUF4200)

    8. XM_039108743.2 → XP_038964671.1  cilia- and flagella-associated protein 100 isoform X4

      Conserved Domains (2) summary
      TIGR02169
      Location:123 → 363
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam13863
      Location:152 → 270
      DUF4200; Domain of unknown function (DUF4200)

    9. XM_039108744.2 → XP_038964672.1  cilia- and flagella-associated protein 100 isoform X5

      UniProtKB/TrEMBL
      A6IB79
      Conserved Domains (1) summary
      pfam13863
      Location:63 → 181
      DUF4200; Domain of unknown function (DUF4200)

    10. XM_039108746.2 → XP_038964674.1  cilia- and flagella-associated protein 100 isoform X8

      UniProtKB/TrEMBL
      A6IB79
      Conserved Domains (1) summary
      pfam13863
      Location:14 → 66
      DUF4200; Domain of unknown function (DUF4200)

    11. XM_063286971.1 → XP_063143041.1  cilia- and flagella-associated protein 100 isoform X9

    12. XM_063286970.1 → XP_063143040.1  cilia- and flagella-associated protein 100 isoform X7

    13. XM_039108747.2 → XP_038964675.1  cilia- and flagella-associated protein 100 isoform X10

      Conserved Domains (1) summary
      pfam13863
      Location:152 → 270
      DUF4200; Domain of unknown function (DUF4200)

    RNA

    1. XR_005503732.2 RNA Sequence

    2. XR_005503731.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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