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    Ubap2 ubiquitin-associated protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313169, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ubap2provided by RGD
    Official Full Name
    ubiquitin-associated protein 2provided by RGD
    Primary source
    RGD:1311717
    See related
    EnsemblRapid:ENSRNOG00000052087 AllianceGenome:RGD:1311717
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in cytoplasm and nucleus. Orthologous to human UBAP2 (ubiquitin associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 57.4), Spleen (RPKM 40.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ubap2 in Genome Data Viewer
    Location:
    5q22
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (61144182..61233355, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (56348243..56437403, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (57534056..57632337, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene nucleolar protein 6 Neighboring gene uncharacterized LOC120103060 Neighboring gene ubiquitin-conjugating enzyme E2R 2 Neighboring gene small nucleolar RNA, C/D box 121B Neighboring gene small nucleolar RNA SNORD121A Neighboring gene small nucleolar RNA, C/D box 121A Neighboring gene ribosomal protein S13 like 1 Neighboring gene DDB1 and CUL4 associated factor 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Guo Z, et al. Sci Signal, 2014 Dec 2. PMID 25468996, Free PMC Article
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-associated protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107928.2 → NP_001101398.2  ubiquitin-associated protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A0U1RRQ3, A6IIU0
      Related
      ENSRNOP00000070607.2, ENSRNOT00000080295.3
      Conserved Domains (2) summary
      cd14277
      Location:53 → 90
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:512 → 541
      DUF3697; Ubiquitin-associated protein 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      61144182..61233355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109842.2 → XP_038965770.1  ubiquitin-associated protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A0U1RRQ3, A6IIU0
      Conserved Domains (2) summary
      cd14277
      Location:53 → 90
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:512 → 541
      DUF3697; Ubiquitin-associated protein 2

    2. XM_063287609.1 → XP_063143679.1  ubiquitin-associated protein 2 isoform X4

      UniProtKB/TrEMBL
      A6IIU0

    3. XM_063287606.1 → XP_063143676.1  ubiquitin-associated protein 2 isoform X3

      UniProtKB/TrEMBL
      A6IIU0

    4. XM_063287614.1 → XP_063143684.1  ubiquitin-associated protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A0U1RRQ3, A6IIU0

    5. XM_063287610.1 → XP_063143680.1  ubiquitin-associated protein 2 isoform X4

      UniProtKB/TrEMBL
      A6IIU0

    6. XM_039109838.2 → XP_038965766.1  ubiquitin-associated protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A0G2JYI7, A6IIU0
      Related
      ENSRNOP00000075769.2, ENSRNOT00000092581.3
      Conserved Domains (2) summary
      cd14277
      Location:59 → 96
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:518 → 547
      DUF3697; Ubiquitin-associated protein 2

    7. XM_063287605.1 → XP_063143675.1  ubiquitin-associated protein 2 isoform X3

      UniProtKB/TrEMBL
      A6IIU0

    8. XM_063287611.1 → XP_063143681.1  ubiquitin-associated protein 2 isoform X4

      UniProtKB/TrEMBL
      A6IIU0

    9. XM_063287615.1 → XP_063143685.1  ubiquitin-associated protein 2 isoform X9

      UniProtKB/TrEMBL
      A6IIU0

    10. XM_063287613.1 → XP_063143683.1  ubiquitin-associated protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A0U1RRQ3, A6IIU0

    11. XM_063287608.1 → XP_063143678.1  ubiquitin-associated protein 2 isoform X4

      UniProtKB/TrEMBL
      A6IIU0

    12. XM_063287607.1 → XP_063143677.1  ubiquitin-associated protein 2 isoform X3

      UniProtKB/TrEMBL
      A6IIU0

    13. XM_017593356.3 → XP_017448845.1  ubiquitin-associated protein 2 isoform X11

      UniProtKB/TrEMBL
      A6IIU0
      Conserved Domains (2) summary
      cd14277
      Location:15 → 52
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:474 → 503
      DUF3697; Ubiquitin-associated protein 2

    14. XM_063287616.1 → XP_063143686.1  ubiquitin-associated protein 2 isoform X10

      UniProtKB/TrEMBL
      A6IIU0

    15. XM_063287604.1 → XP_063143674.1  ubiquitin-associated protein 2 isoform X2

      UniProtKB/TrEMBL
      A6IIU0

    16. XM_063287603.1 → XP_063143673.1  ubiquitin-associated protein 2 isoform X1

      UniProtKB/TrEMBL
      A6IIU0

    17. XM_006238054.4 → XP_006238116.2  ubiquitin-associated protein 2 isoform X6

      UniProtKB/TrEMBL
      A6IIU0

    18. XM_063287612.1 → XP_063143682.1  ubiquitin-associated protein 2 isoform X5

      UniProtKB/TrEMBL
      A6IIU0
      Related
      ENSRNOP00000070670.2, ENSRNOT00000080787.3
    Nucleotide Protein Strain
    Heading Accession and Version

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