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    Zfp878 zinc finger protein 878 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102548917, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp878provided by RGD
    Official Full Name
    zinc finger protein 878provided by RGD
    Primary source
    RGD:7600751
    See related
    EnsemblRapid:ENSRNOG00000060701 AllianceGenome:RGD:7600751
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Orthologous to human ZNF878 (zinc finger protein 878). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 91.5), Kidney (RPKM 67.5) and 9 other tissues See more
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    Genomic context

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    See Zfp878 in Genome Data Viewer
    Location:
    16p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (17890878..17920716, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (17856860..17887122, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (19580839..19592455, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 18 Neighboring gene zinc finger protein 617 Neighboring gene uncharacterized LOC102548752 Neighboring gene uncharacterized LOC134482464 Neighboring gene zinc finger protein 709 Neighboring gene HAUS augmin-like complex, subunit 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • AC130232.2

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 844-like
    Names
    zinc finger protein 490
    zinc finger protein 709

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001409026.1 → NP_001395955.1  zinc finger protein 844-like

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A0A0G2KB80, A6K9R3
      Related
      ENSRNOP00000084864.2, ENSRNOT00000112727.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      17890878..17920716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095184.2 → XP_038951112.1  zinc finger protein 844-like isoform X1

      Conserved Domains (6) summary
      COG3767
      Location:174 → 215
      COG3767; Uncharacterized low-complexity protein [Function unknown]
      COG5048
      Location:429 → 606
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:339 → 414
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:86 → 123
      KRAB; KRAB box
      pfam13465
      Location:321 → 346
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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