Abca17 ATP-binding cassette, subfamily A (ABC1), member 17 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Abca17provided by RGD
Official Full Name: ATP-binding cassette, subfamily A (ABC1), member 17provided by RGD
Primary source: RGD:1560494
See related: EnsemblRapid:ENSRNOG00000039656 AllianceGenome:RGD:1560494
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 47.6), Lung (RPKM 26.6) and 4 other tissues See more
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Genomic context

Location:: 10q12

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (13793810..13886718, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (13289246..13382221, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (13630076..13723155, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The cloning and characterization of ABCA17 is reported.
Title: Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables lipid transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in lipid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in neutral lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP-binding cassette sub-family A member 17

Names: ATP-binding cassette, sub-family A (ABC1), member 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031637.1 → NP_001026807.1 ATP-binding cassette sub-family A member 17

See identical proteins and their annotated locations for NP_001026807.1

Status: PROVISIONAL

Source sequence(s)

AB196699

UniProtKB/TrEMBL

A0A8I6A6S8

Related

ENSRNOP00000086705.1, ENSRNOT00000112988.2

Conserved Domains (4) summary

TIGR01188
Location:543 → 834

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:525 → 746

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:1369 → 1682

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:913 → 1255

ABC2_membrane_3; ABC-2 family transporter protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

13793810..13886718 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008767557.4 → XP_008765779.1 ATP-binding cassette sub-family A member 17 isoform X5

UniProtKB/TrEMBL

A0A8I6A6S8

Conserved Domains (5) summary

TIGR01188
Location:543 → 834

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:525 → 746

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:1335 → 1648

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:913 → 1149

ABC2_membrane_3; ABC-2 family transporter protein

cl21474
Location:254 → 415

ABC2_membrane; ABC-2 type transporter
XM_039085351.2 → XP_038941279.1 ATP-binding cassette sub-family A member 17 isoform X4

UniProtKB/TrEMBL

A0A8I6A6S8

Conserved Domains (1) summary

TIGR01257
Location:209 → 1654

rim_protein; retinal-specific rim ABC transporter
XM_008767555.4 → XP_008765777.1 ATP-binding cassette sub-family A member 17 isoform X2

UniProtKB/TrEMBL

A0A8I6A6S8

Conserved Domains (5) summary

TIGR01188
Location:543 → 834

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:525 → 746

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:1362 → 1675

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:913 → 1248

ABC2_membrane_3; ABC-2 family transporter protein

cl01738
Location:304 → 394

DUF898; Bacterial protein of unknown function (DUF898)
XM_006245928.5 → XP_006245990.1 ATP-binding cassette sub-family A member 17 isoform X1

See identical proteins and their annotated locations for XP_006245990.1

UniProtKB/Swiss-Prot

E9PU17, Q4H493

UniProtKB/TrEMBL

A0A8I6A6S8

Conserved Domains (5) summary

TIGR01188
Location:543 → 834

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:525 → 746

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:1369 → 1682

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:913 → 1255

ABC2_membrane_3; ABC-2 family transporter protein

cl01738
Location:304 → 394

DUF898; Bacterial protein of unknown function (DUF898)
XM_006245927.5 → XP_006245989.1 ATP-binding cassette sub-family A member 17 isoform X1

See identical proteins and their annotated locations for XP_006245989.1

UniProtKB/Swiss-Prot

E9PU17, Q4H493

UniProtKB/TrEMBL

A0A8I6A6S8

Related

ENSRNOP00000057544.2, ENSRNOT00000060818.4

Conserved Domains (5) summary

TIGR01188
Location:543 → 834

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:525 → 746

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:1369 → 1682

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:913 → 1255

ABC2_membrane_3; ABC-2 family transporter protein

cl01738
Location:304 → 394

DUF898; Bacterial protein of unknown function (DUF898)
XM_008767556.4 → XP_008765778.1 ATP-binding cassette sub-family A member 17 isoform X3

UniProtKB/TrEMBL

A0A8I6A6S8

Conserved Domains (5) summary

TIGR01188
Location:513 → 804

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:495 → 716

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:1339 → 1652

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:883 → 1225

ABC2_membrane_3; ABC-2 family transporter protein

cl01738
Location:274 → 364

DUF898; Bacterial protein of unknown function (DUF898)
XM_063268557.1 → XP_063124627.1 ATP-binding cassette sub-family A member 17 isoform X6

UniProtKB/TrEMBL

A0A8I6A6S8
XM_039085353.2 → XP_038941281.1 ATP-binding cassette sub-family A member 17 isoform X7

UniProtKB/TrEMBL

A0A8I6A6S8

Conserved Domains (1) summary

TIGR01257
Location:18 → 1466

rim_protein; retinal-specific rim ABC transporter
XM_039085354.2 → XP_038941282.1 ATP-binding cassette sub-family A member 17 isoform X8

Conserved Domains (1) summary

TIGR01257
Location:65 → 1385

rim_protein; retinal-specific rim ABC transporter
XM_063268561.1 → XP_063124631.1 ATP-binding cassette sub-family A member 17 isoform X11
XM_063268560.1 → XP_063124630.1 ATP-binding cassette sub-family A member 17 isoform X10
XM_063268558.1 → XP_063124628.1 ATP-binding cassette sub-family A member 17 isoform X9
XM_039085355.2 → XP_038941283.1 ATP-binding cassette sub-family A member 17 isoform X12

Conserved Domains (1) summary

TIGR01257
Location:209 → 1141

rim_protein; retinal-specific rim ABC transporter