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    Abhd18 abhydrolase domain containing 18 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499602, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Abhd18provided by RGD
    Official Full Name
    abhydrolase domain containing 18provided by RGD
    Primary source
    RGD:1563987
    See related
    EnsemblRapid:ENSRNOG00000013692 AllianceGenome:RGD:1563987
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in mitochondrion. Orthologous to human ABHD18 (abhydrolase domain containing 18). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 135.9), Muscle (RPKM 58.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Abhd18 in Genome Data Viewer
    Location:
    2q26
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (125800488..125850167)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (123872299..123920987)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (127770588..127828218)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene polo-like kinase 4 Neighboring gene major facilitator superfamily domain containing 8 Neighboring gene FUN14 domain containing 2, pseudogene 1 Neighboring gene FUN14 domain containing 2B Neighboring gene La ribonucleoprotein 1B Neighboring gene La ribonucleoprotein 1B like Neighboring gene uncharacterized LOC134485903

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein ABHD18
    Names
    abhydrolase domain-containing protein 18
    alpha/beta hydrolase domain-containing protein 18
    uncharacterized protein C4orf29 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025039.2 → NP_001020210.2  protein ABHD18 precursor

      Status: PROVISIONAL

      Source sequence(s)
      BC086604, BC098046, CB612934, CK358190
      UniProtKB/Swiss-Prot
      Q4V7A8, Q5RJK2
      Related
      ENSRNOP00000076238.3, ENSRNOT00000093644.3
      Conserved Domains (1) summary
      pfam09752
      Location:16 → 457
      DUF2048; Uncharacterized conserved protein (DUF2048)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      125800488..125850167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102873.2 → XP_038958801.1  protein ABHD18 isoform X1

      UniProtKB/TrEMBL
      A6II41
      Conserved Domains (1) summary
      cl21494
      Location:1 → 288
      Abhydrolase; alpha/beta hydrolases

    2. XM_039102874.2 → XP_038958802.1  protein ABHD18 isoform X1

      UniProtKB/TrEMBL
      A6II41
      Conserved Domains (1) summary
      cl21494
      Location:1 → 288
      Abhydrolase; alpha/beta hydrolases

    3. XM_063282363.1 → XP_063138433.1  protein ABHD18 isoform X1

      UniProtKB/TrEMBL
      A6II41

    4. XM_063282362.1 → XP_063138432.1  protein ABHD18 isoform X1

      UniProtKB/TrEMBL
      A6II41

    5. XM_063282364.1 → XP_063138434.1  protein ABHD18 isoform X2

      UniProtKB/TrEMBL
      A6II41

    RNA

    1. XR_010063640.1 RNA Sequence

    2. XR_010063639.1 RNA Sequence

    3. XR_010063638.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V7A8.2 GenPept UniProtKB/Swiss-Prot:Q4V7A8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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