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    Vom2r52 vomeronasal 2 receptor, 52 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297590, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vom2r52provided by RGD
    Official Full Name
    vomeronasal 2 receptor, 52provided by RGD
    Primary source
    RGD:735022
    See related
    EnsemblRapid:ENSRNOG00000068988 AllianceGenome:RGD:735022
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vom2r52 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (158603601..158642225, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (156918262..156956543, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (156597780..156629949, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene vomeronasal 2 receptor, 50 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene vomeronasal 2 receptor, 51 Neighboring gene uncharacterized LOC134486636 Neighboring gene complement C1s, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A new multigene family of putative pheromone receptors. Ryba NJ, et al. Neuron, 1997 Aug. PMID 9292726
    2. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2 receptor, 52
    Names
    putative pheromone receptor V2R1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099503.1 → NP_001092973.1  vomeronasal 2 receptor, 52 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      F1MAT0
      Related
      ENSRNOP00000048953.6, ENSRNOT00000042249.7
      Conserved Domains (4) summary
      pfam00003
      Location:611 → 845
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam05873
      Location:81 → 171
      Mt_ATP-synt_D; ATP synthase D chain, mitochondrial (ATP5H)
      pfam07562
      Location:526 → 576
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:178 → 516
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      158603601..158642225 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039107446.2 → XP_038963374.1  vomeronasal 2 receptor, 52 isoform X1

      UniProtKB/TrEMBL
      F1MAJ6
      Conserved Domains (3) summary
      cd15283
      Location:590 → 841
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:39 → 509
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:517 → 570
      NCD3G; Nine Cysteines Domain of family 3 GPCR
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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