Bcas2 BCAS2, pre-mRNA processing factor [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bcas2provided by RGD
Official Full Name: BCAS2, pre-mRNA processing factorprovided by RGD
Primary source: RGD:1306485
See related: EnsemblRapid:ENSRNOG00000018783 AllianceGenome:RGD:1306485
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in centrosome and nuclear speck. Predicted to be part of DNA replication factor A complex; Prp19 complex; and U2-type catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human BCAS2 (BCAS2 pre-mRNA processing factor). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 589.2), Heart (RPKM 274.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q34

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (193381000..193388881)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (190692503..190700386)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (205662633..205670514)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in alternative mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within alternative mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info
involved_in mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info
involved_in oocyte development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within oocyte development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within oogenesis	ISO Inferred from Sequence Orthology more info
involved_in ovarian follicle development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ovarian follicle development	ISO Inferred from Sequence Orthology more info
involved_in protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein catabolic process	ISO Inferred from Sequence Orthology more info
involved_in spindle assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within spindle assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of DNA replication factor A complex	ISO Inferred from Sequence Orthology more info
part_of Prp19 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Prp19 complex	ISO Inferred from Sequence Orthology more info
part_of U2-type catalytic step 2 spliceosome	ISO Inferred from Sequence Orthology more info
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of spliceosomal complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: pre-mRNA-splicing factor SPF27

Names: breast carcinoma amplified sequence 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.