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GenBank: X67108.1
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LOCUS X67108 3675 bp mRNA linear ROD 18-APR-2005 DEFINITION R.norvegicus mRNA for brain-derived neurotrophic factor (exon IV). ACCESSION X67108 VERSION X67108.1 KEYWORDS brain-derived neurotrophic factor; neurotrophic factor. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 AUTHORS Timmusk,T., Palm,K., Metsis,M., Reintam,T., Paalme,V., Saarma,M. and Persson,H. TITLE Multiple promoters direct tissue-specific expression of the rat BDNF gene JOURNAL Neuron 10 (3), 475-489 (1993) PUBMED 8461137 REFERENCE 2 (bases 1 to 3675) AUTHORS Metsis,M. TITLE Direct Submission JOURNAL Submitted (22-JUN-1992) M. Metsis, Dept. of Medical Chemistry, Lab. of Molecular Neurobiology, Karolinska Institute, Box 604 00, 10401 Stockholm, SWEDEN FEATURES Location/Qualifiers source 1..3675 /organism="Rattus norvegicus" /mol_type="mRNA" /db_xref="taxon:10116" /clone_lib="rat hippocampal cDNA library" gene 1..3675 /gene="BDNF gene" CDS 43..771 /gene="BDNF gene" /codon_start=1 /product="brain-derived neurotrophic factor" /protein_id="CAA47481.1" /db_xref="GOA:P23363" /db_xref="InterPro:IPR002072" /db_xref="InterPro:IPR019846" /db_xref="InterPro:IPR020408" /db_xref="InterPro:IPR020430" /db_xref="UniProtKB/Swiss-Prot:P23363" /translation="MVISYFGCMKAAPMKEANVHGQGNLAYPAVRTHGTLESVNGPRA GSRGLTTTSLADTFEHVIEELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLL FLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVT VLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSK KRIGWRFIRIDTSCVCTLTIKRGR" regulatory 1087..1092 /regulatory_class="polyA_signal_sequence" /gene="BDNF gene" /note="for shorter transcripts" regulatory 3670..3675 /regulatory_class="polyA_signal_sequence" /gene="BDNF gene" /experiment="experimental evidence, no additional details recorded" /note="polyA tail" ORIGIN 1 ttccaccagg tgagaagagt gatgaccatc cttttcctta ctatggttat ttcatacttc 61 ggttgcatga aggctgcgcc catgaaagaa gcaaacgtcc acggacaagg caacttggcc 121 tacccagctg tgcggaccca tgggactctg gagagcgtga atgggcccag ggcaggttcg 181 agaggtctga cgacgacgtc cctggctgac acttttgagc acgtgatcga agagctgctg 241 gatgaggacc agaaggttcg gcccaacgaa gaaaaccata aggacgcgga cttgtacact 301 tcccgggtga tgctcagcag tcaagtgcct ttggagcctc ctctgctctt tctgctggag 361 gaatacaaaa attacctgga tgccgcaaac atgtctatga gggttcggcg ccactccgac 421 cccgcccgcc gtggggagct gagcgtgtgt gacagtatta gcgagtgggt cacagcggca 481 gataaaaaga ctgcagtgga catgtccggt gggacggtca cagtcctgga gaaagtcccg 541 gtatcaaaag gccaactgaa gcaatatttc tacgagacca agtgtaatcc catgggttac 601 acgaaggaag gctgcagggg catagacaaa aggcactgga actcgcaatg ccgaactacc 661 caatcgtatg ttcgggccct tactatggat agcaaaaaga gaattggctg gcggttcata 721 aggatagaca cttcctgtgt atgtacactg accattaaaa ggggaagata gtggatttat 781 gttgtataga ttatattgag acaaaaatta tctatttgta tatatacata acagggtaaa 841 ttattcagtt aagaaaaaga taattttatg aactgcatgt ataaatgaag tttatacagt 901 acagtggttc tacaatctat ttattggaca tatccatgac cagaaagaaa cagtcatttg 961 cgcacaactt taaaagtctg cattacattc ctcgataatg ttgtggtttg ttgccgttgc 1021 caagaattga aaacaaaaag ttaaaaaaaa taataaattg catgctgctt taattgtgaa 1081 ttgataataa actgtccctc tttcagaaaa cagacaaaaa aacaaaaaac aaaaaaaggc 1141 aaaaacaaaa atttgaacca aaacattccg tttacatttt agacactaag tatcttcgtt 1201 cttgttagta ctctgttcta ctgctttcaa cttctcatag cgttggaatt aaaactatgt 1261 caaggtgctg ttgtcattgc tttactggct taggggatgg ggaacgggag gggtagattt 1321 ctgtttgttt tgtgttttat ttcgtttgtt tgtttgtttt gtttttttag ttccacccgg 1381 agtagggatg gagaaaattt cttcactctc cattctggtt gataaagcgt tacatttgta 1441 tgttgtaaaa aatgtttgca aaatccaatc agatgactgg aaaacgaata aaaattaagg 1501 caactgaata aaatgctcac acaacactgc ccatgatgta tctccctggt cccccaggtc 1561 actcttctgg catgggtcag ggaaagctgc ttttattgga aagaccagca tttgtttaaa 1621 gcacattctt tccctccctc ctcccatttt ggtccctttc ttttttgttt tgttttaaga 1681 aagaaaatta agttgcgcgc tttgaaatat tttatcactg ctgtgaacag atgaacaatg 1741 tgtgtcattt catgacactc gtggaaaaca gtgatttttt ttttattttt tgccctaagg 1801 agaaacaagt aagaataacc gaaaatgttc ttttttttta aaggcataaa cagtggataa 1861 gttataatat ggcctaacaa tgtttgcaga taaaagatat tgcatacagc cagatactag 1921 agcagggatc cacactgcca ctgaaatgcg actgaatggc cctgtggagg ctaagtggag 1981 ctgacatact atttcctggc agagcaggag gaatttctga gtggccatcc tgaggtctag 2041 atggaggtgg ggaatggtac ttgagacatt cctaaaggaa ggctcggaag cacccttcag 2101 agcaggctct ggaatgatgt gtcaagtttc ttaggccttc tgctttaagt gcctacgtta 2161 ggtaacagtg ctcaagaggt tctcaattgg agaaccacac tcaaatccat ttatggcctc 2221 catcccattt taaataatta tggataaagt tggattaacc tggagcagct ttggatccaa 2281 atatggcata gcagtgatgc tatcagtgca gcatgatggg aaatgtttgc tgtgaagaga 2341 cttaactttc tttgcgctta gacttcagga agcctaggtt ttatttattt atttttttga 2401 gacattttgg tgaaaggaaa aaagaaagaa gaaaacaaac aaacaaaacc agaaaaagca 2461 ccaaaactta ggcagaatga gcaatgtctg tctgtaaggg ctagaatgac aaggcatagg 2521 aaggtgcttt cactgtgaaa gagacaagaa cacaggagga aatactgctt aagtgaagag 2581 cacagaaagc tcctgatagt tctgtccatt cagcacaagg gtcccttcta cactttacct 2641 cttggggtta ggagaagtca agctggaagc ctgaatgaat ggccccaatg agaactagtg 2701 ttaagcccat ttccctagtg aggttttccg ccacgcgaat gtgttagtgg ttacctgact 2761 gggctcctgg gcatcagaaa aagaggcaaa caattgcttc atcttaggag tggaaagggt 2821 gaaacaaagt ggctgtccac tgtgactcag ggagtgaaga taccatcagc aaatagtttc 2881 tttttgttca actgttcctt tagaactagt ctgtcttctg gagtcccact gaatcccctg 2941 tttttggaag acttcacgta gcctagattg ttttgtgcct ttgacaacat taatctctgt 3001 catcattttt aacctattaa ggaatgcttt gaatatctgc tatatgctaa ctttttgcag 3061 cttcattctg agagacgtta gtcaaacaaa taaaaggagc cccatcacaa tctcacggta 3121 ttgcaagggc caggtcgatt aggtggcttc ataggagacc ctccgcaact gtgtggtcag 3181 tggctggctc tcatacccac taagatacat catagctcca tgtcggtggt ttatgttgac 3241 tctaactaaa caattttaga gaggagacaa agacaagcaa gacaaaggca ggacaagaca 3301 agacaagaca agactttcag aacgacacca gagaaaaacc gtcttcacaa agtacgtacc 3361 gtcgtccgga ctacgaaaaa tatcactaag ggtaactttg acattcattt acagacaccg 3421 gaacaagaga gatacccatt tctataataa gtggtacatt ttgttctttt tataaataac 3481 ataaaatcat ataaatatat taatacaata acttttttta accgtaattt tgaattggtg 3541 tagtcttcgg ataacattta tgtccaagat aaattcacat ggttaattgt atattatata 3601 caaaatttat atcttaaaaa ttacaaaaat ttatataaaa gtttcatgta ttttagaccc 3661 ccaagaccca aaaaa //
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