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R.norvegicus mRNA for brain-derived neurotrophic factor (exon IV)

GenBank: X67108.1

FASTA Graphics 

LOCUS       X67108                  3675 bp    mRNA    linear   ROD 18-APR-2005
DEFINITION  R.norvegicus mRNA for brain-derived neurotrophic factor (exon IV).
ACCESSION   X67108
VERSION     X67108.1
KEYWORDS    brain-derived neurotrophic factor; neurotrophic factor.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1
  AUTHORS   Timmusk,T., Palm,K., Metsis,M., Reintam,T., Paalme,V., Saarma,M.
            and Persson,H.
  TITLE     Multiple promoters direct tissue-specific expression of the rat
            BDNF gene
  JOURNAL   Neuron 10 (3), 475-489 (1993)
   PUBMED   8461137
REFERENCE   2  (bases 1 to 3675)
  AUTHORS   Metsis,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JUN-1992) M. Metsis, Dept. of Medical Chemistry, Lab.
            of Molecular Neurobiology, Karolinska Institute, Box 604 00, 10401
            Stockholm, SWEDEN
FEATURES             Location/Qualifiers
     source          1..3675
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /clone_lib="rat hippocampal cDNA library"
     gene            1..3675
                     /gene="BDNF gene"
     CDS             43..771
                     /gene="BDNF gene"
                     /codon_start=1
                     /product="brain-derived neurotrophic factor"
                     /protein_id="CAA47481.1"
                     /db_xref="GOA:P23363"
                     /db_xref="InterPro:IPR002072"
                     /db_xref="InterPro:IPR019846"
                     /db_xref="InterPro:IPR020408"
                     /db_xref="InterPro:IPR020430"
                     /db_xref="UniProtKB/Swiss-Prot:P23363"
                     /translation="MVISYFGCMKAAPMKEANVHGQGNLAYPAVRTHGTLESVNGPRA
                     GSRGLTTTSLADTFEHVIEELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLL
                     FLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVT
                     VLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSK
                     KRIGWRFIRIDTSCVCTLTIKRGR"
     regulatory      1087..1092
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BDNF gene"
                     /note="for shorter transcripts"
     regulatory      3670..3675
                     /regulatory_class="polyA_signal_sequence"
                     /gene="BDNF gene"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="polyA tail"
ORIGIN      
        1 ttccaccagg tgagaagagt gatgaccatc cttttcctta ctatggttat ttcatacttc
       61 ggttgcatga aggctgcgcc catgaaagaa gcaaacgtcc acggacaagg caacttggcc
      121 tacccagctg tgcggaccca tgggactctg gagagcgtga atgggcccag ggcaggttcg
      181 agaggtctga cgacgacgtc cctggctgac acttttgagc acgtgatcga agagctgctg
      241 gatgaggacc agaaggttcg gcccaacgaa gaaaaccata aggacgcgga cttgtacact
      301 tcccgggtga tgctcagcag tcaagtgcct ttggagcctc ctctgctctt tctgctggag
      361 gaatacaaaa attacctgga tgccgcaaac atgtctatga gggttcggcg ccactccgac
      421 cccgcccgcc gtggggagct gagcgtgtgt gacagtatta gcgagtgggt cacagcggca
      481 gataaaaaga ctgcagtgga catgtccggt gggacggtca cagtcctgga gaaagtcccg
      541 gtatcaaaag gccaactgaa gcaatatttc tacgagacca agtgtaatcc catgggttac
      601 acgaaggaag gctgcagggg catagacaaa aggcactgga actcgcaatg ccgaactacc
      661 caatcgtatg ttcgggccct tactatggat agcaaaaaga gaattggctg gcggttcata
      721 aggatagaca cttcctgtgt atgtacactg accattaaaa ggggaagata gtggatttat
      781 gttgtataga ttatattgag acaaaaatta tctatttgta tatatacata acagggtaaa
      841 ttattcagtt aagaaaaaga taattttatg aactgcatgt ataaatgaag tttatacagt
      901 acagtggttc tacaatctat ttattggaca tatccatgac cagaaagaaa cagtcatttg
      961 cgcacaactt taaaagtctg cattacattc ctcgataatg ttgtggtttg ttgccgttgc
     1021 caagaattga aaacaaaaag ttaaaaaaaa taataaattg catgctgctt taattgtgaa
     1081 ttgataataa actgtccctc tttcagaaaa cagacaaaaa aacaaaaaac aaaaaaaggc
     1141 aaaaacaaaa atttgaacca aaacattccg tttacatttt agacactaag tatcttcgtt
     1201 cttgttagta ctctgttcta ctgctttcaa cttctcatag cgttggaatt aaaactatgt
     1261 caaggtgctg ttgtcattgc tttactggct taggggatgg ggaacgggag gggtagattt
     1321 ctgtttgttt tgtgttttat ttcgtttgtt tgtttgtttt gtttttttag ttccacccgg
     1381 agtagggatg gagaaaattt cttcactctc cattctggtt gataaagcgt tacatttgta
     1441 tgttgtaaaa aatgtttgca aaatccaatc agatgactgg aaaacgaata aaaattaagg
     1501 caactgaata aaatgctcac acaacactgc ccatgatgta tctccctggt cccccaggtc
     1561 actcttctgg catgggtcag ggaaagctgc ttttattgga aagaccagca tttgtttaaa
     1621 gcacattctt tccctccctc ctcccatttt ggtccctttc ttttttgttt tgttttaaga
     1681 aagaaaatta agttgcgcgc tttgaaatat tttatcactg ctgtgaacag atgaacaatg
     1741 tgtgtcattt catgacactc gtggaaaaca gtgatttttt ttttattttt tgccctaagg
     1801 agaaacaagt aagaataacc gaaaatgttc ttttttttta aaggcataaa cagtggataa
     1861 gttataatat ggcctaacaa tgtttgcaga taaaagatat tgcatacagc cagatactag
     1921 agcagggatc cacactgcca ctgaaatgcg actgaatggc cctgtggagg ctaagtggag
     1981 ctgacatact atttcctggc agagcaggag gaatttctga gtggccatcc tgaggtctag
     2041 atggaggtgg ggaatggtac ttgagacatt cctaaaggaa ggctcggaag cacccttcag
     2101 agcaggctct ggaatgatgt gtcaagtttc ttaggccttc tgctttaagt gcctacgtta
     2161 ggtaacagtg ctcaagaggt tctcaattgg agaaccacac tcaaatccat ttatggcctc
     2221 catcccattt taaataatta tggataaagt tggattaacc tggagcagct ttggatccaa
     2281 atatggcata gcagtgatgc tatcagtgca gcatgatggg aaatgtttgc tgtgaagaga
     2341 cttaactttc tttgcgctta gacttcagga agcctaggtt ttatttattt atttttttga
     2401 gacattttgg tgaaaggaaa aaagaaagaa gaaaacaaac aaacaaaacc agaaaaagca
     2461 ccaaaactta ggcagaatga gcaatgtctg tctgtaaggg ctagaatgac aaggcatagg
     2521 aaggtgcttt cactgtgaaa gagacaagaa cacaggagga aatactgctt aagtgaagag
     2581 cacagaaagc tcctgatagt tctgtccatt cagcacaagg gtcccttcta cactttacct
     2641 cttggggtta ggagaagtca agctggaagc ctgaatgaat ggccccaatg agaactagtg
     2701 ttaagcccat ttccctagtg aggttttccg ccacgcgaat gtgttagtgg ttacctgact
     2761 gggctcctgg gcatcagaaa aagaggcaaa caattgcttc atcttaggag tggaaagggt
     2821 gaaacaaagt ggctgtccac tgtgactcag ggagtgaaga taccatcagc aaatagtttc
     2881 tttttgttca actgttcctt tagaactagt ctgtcttctg gagtcccact gaatcccctg
     2941 tttttggaag acttcacgta gcctagattg ttttgtgcct ttgacaacat taatctctgt
     3001 catcattttt aacctattaa ggaatgcttt gaatatctgc tatatgctaa ctttttgcag
     3061 cttcattctg agagacgtta gtcaaacaaa taaaaggagc cccatcacaa tctcacggta
     3121 ttgcaagggc caggtcgatt aggtggcttc ataggagacc ctccgcaact gtgtggtcag
     3181 tggctggctc tcatacccac taagatacat catagctcca tgtcggtggt ttatgttgac
     3241 tctaactaaa caattttaga gaggagacaa agacaagcaa gacaaaggca ggacaagaca
     3301 agacaagaca agactttcag aacgacacca gagaaaaacc gtcttcacaa agtacgtacc
     3361 gtcgtccgga ctacgaaaaa tatcactaag ggtaactttg acattcattt acagacaccg
     3421 gaacaagaga gatacccatt tctataataa gtggtacatt ttgttctttt tataaataac
     3481 ataaaatcat ataaatatat taatacaata acttttttta accgtaattt tgaattggtg
     3541 tagtcttcgg ataacattta tgtccaagat aaattcacat ggttaattgt atattatata
     3601 caaaatttat atcttaaaaa ttacaaaaat ttatataaaa gtttcatgta ttttagaccc
     3661 ccaagaccca aaaaa
//
43..771
/gene="BDNF gene"
/codon_start=1
/product="brain-derived neurotrophic factor"
/protein_id="CAA47481.1"
/db_xref="GOA:P23363"
/db_xref="InterPro:IPR002072"
/db_xref="InterPro:IPR019846"
/db_xref="InterPro:IPR020408"
/db_xref="InterPro:IPR020430"
/db_xref="UniProtKB/Swiss-Prot:P23363"
/translation="MVISYFGCMKAAPMKEANVHGQGNLAYPAVRTHGTLESVNGPRA
GSRGLTTTSLADTFEHVIEELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLL
FLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVT
VLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSK
KRIGWRFIRIDTSCVCTLTIKRGR"
Feature X67108 : 1 segment
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