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    Fndc3c1 fibronectin type III domain containing 3C1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317224, updated on 9-Dec-2024

    Summary

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    Symbol
    Fndc3c1provided by RGD
    Full Name
    fibronectin type III domain containing 3C1provided by RGD
    Primary source
    RGD:1563846
    See related
    EnsemblRapid:ENSRNOG00000002451 AllianceGenome:RGD:1563846
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561693; RGD1563846
    Summary
    Predicted to be involved in spermatid development. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 36.2), Testes (RPKM 5.0) and 1 other tissue See more
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    Genomic context

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    See Fndc3c1 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (75562242..75630812, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (71489374..71547160, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (77416959..77559348, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene igE-binding protein-like Neighboring gene fibronectin type III domain containing protein 3C1-like Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene ribosomal protein L7, pseudogene 30

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    fibronectin type III domain containing protein 3C1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191722.1 → NP_001178651.1  fibronectin type III domain containing protein 3C1

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A0U1RRN5
      Conserved Domains (3) summary
      COG5422
      Location:229 → 520
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      cd00063
      Location:1031 → 1104
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam16656
      Location:465 → 551
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      75562242..75630812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280022.1 → XP_063136092.1  fibronectin type III domain containing protein 3C1 isoform X1

      UniProtKB/TrEMBL
      A0A0U1RRN5

    2. XM_063280023.1 → XP_063136093.1  fibronectin type III domain containing protein 3C1 isoform X1

      UniProtKB/TrEMBL
      A0A0U1RRN5
      Related
      ENSRNOP00000108182.1, ENSRNOT00000173384.1

    3. XM_039099739.2 → XP_038955667.1  fibronectin type III domain containing protein 3C1 isoform X2

      Related
      ENSRNOP00000075748.3, ENSRNOT00000092505.3
      Conserved Domains (3) summary
      COG5422
      Location:229 → 520
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      cd00063
      Location:993 → 1066
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam16656
      Location:465 → 551
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain

    4. XM_039099738.2 → XP_038955666.1  fibronectin type III domain containing protein 3C1 isoform X1

      UniProtKB/TrEMBL
      A0A0U1RRN5
      Conserved Domains (3) summary
      COG5422
      Location:229 → 520
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      cd00063
      Location:1031 → 1104
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam16656
      Location:465 → 551
      Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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