Conserved Protein Domain Family
7TM_GPCR_Srv

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pfam10323: 7TM_GPCR_Srv 
Serpentine type 7TM GPCR chemoreceptor Srv
Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srv is a member of the Srg superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
Statistics
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PSSM-Id: 370977
Aligned: 25 rows
Threshold Bit Score: 197.072
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9XVM5        19 LFLFTIVTFILYFIEIQIVFSYRKTT---FKGPFYRLLFVGIIVDIISVINMFMGQVVPAQRWFEPFLIRNQNWLGSVFL 95  Caenorhabditis ...
O45353        11 FIYEYFILIPIYIFILLGILITRNRHk-tFQSPYYTMMVSQGLADVCTVTIYIVIIGARYFSIGNVFIYNLSPYSSYSFS 89  Caenorhabditis ...
Q9U316        23 QIILVTVTFPFYIFLLAFIISAQLRNiddLATPFFKLCISSSFIDLTTLLTNYFGAMFPKFGYFFNFYMGLGQIYPHIYL 102 Caenorhabditis ...
XP_002633578  14 QLILVTITVPLYLFLLFFMIKAQIRKvdeLGTPFFKLCITTAIIDLSTLFANYFGAMFPKMGFFADFYRNLDYIYAHIYF 93 
Q86DM4        16 QFAIVTVTVPFYLFLWYFMIKAQFRKfdeLATPFFKLCISTAIIDLSTLFANYFGVMFPKFGFFNDFYIYLDAIYAHIYL 95  Caenorhabditis ...
Q9U312        32 QFSIFCVTISIYLVIVWALIEAQNRRveeLSSPFFKLCLSTAGVDIWTLLTNYLGAMFPKWGWFVSVYLFLGNPYGRIYL 111 Caenorhabditis ...
Q9XU18        31 QFSIFCFTLPFYIFVIYFLVDAQLHGkqeLCTPFFKLCVTTAIIDICTLLNNYLGAMFPKWGWGTGIYIFLDGYCAHFYL 110 Caenorhabditis ...
Q9U306        30 QFSIFCFTLPFYVFVTYFLLDALHRGideLSTPFFRLCITTAFLDIWTLLNNYLGAMFPKWGWGTSVYLFLDSYYAHAYL 109 Caenorhabditis ...
Q23041        22 FMLGSFVTILLYFVEILILVTLRNTV---YKGMFYQIFTIGIIIDVISLVNNYFGCVFPAKGYFRDFYLSMGTFVGQMYL 98  Caenorhabditis ...
P92000        23 LLLLTIVSFLLYFIEIQIIFAYRKTT---FRGPFYRLMFVGIIVDMLSTINMFTGQVIPARRWFEPFLIYNQSWLGSIFF 99  Caenorhabditis ...
Q9XVM5        96 VITYGGRCIQGATAAILSFCRVCAVCFPI-FYRKLGEPCYLFIMQAIQ-LGGGVLAWVLLGPDLYEYILEDDglFAVGSE 173 Caenorhabditis ...
O45353        90 NTGPFMFTLRGVGVFFITTQRYLAVCRSHgTLNYRLNQCPPLLIGFTHwLVAFLIYLPALLHTDIYFENEVT--LLTVGS 167 Caenorhabditis ...
Q9U316       103 YIAWSMGICQAMSVSVLATNRLSAMIFPE-HYRKIWKSNKLWIGVGIQfLPGLGIGCCTFFNTTEIYINGNGgiIPRFID 181 Caenorhabditis ...
XP_002633578  94 YIAWSTGICQAASVSVLATNRLSAIILPQ-SYKKMWHSSRLWIPISIQyVPGMLVGLLTFFNKTTLATNENNglMPQFSD 172
Q86DM4        96 YIAWSTGICQAMCVSVLATNRLSAMLLPG-SYHKMWKSKRLWIAISVQfLPGMLVGLLTFFNKTQLAINEKNglVPVFLD 174 Caenorhabditis ...
Q9U312       112 YFAWSTGICQAMSVSVLASNRLSVMLFPT-SFNRIWQEHRLWIAISIQyLIGLIIGLSTFLNDVQLFRNSKNgiVPRFLN 190 Caenorhabditis ...
Q9XU18       111 YFAWTSVICQAMCVSVLATNRLSAILFPH-RHFQLWNSKRLRIAVLIQfVPGMIAGCATFFNSTQLYRNAKNglVPKFQN 189 Caenorhabditis ...
Q9U306       110 YFAWASGICQAMCVSLMATNRVSAILFPN-RHSRIWSSTRLRIAIAVQfLPGLLAGLATFFNETQLYRNTKNglIPRFKS 188 Caenorhabditis ...
Q23041        99 MIAWTARGIQGCTVVALALNRATAVCLPI-KHKQIWNSKYISLIHVFQlGVGLCIGS-SLITQNFYWKFERNgiYIQFYN 176 Caenorhabditis ...
P92000       100 VITYGGRCIQGATAAILSFCRVCAVCFPI-FYHKLGEPWYLHTMQAVQ-LAGGVIAFVILWPDSYEYILEDNcfYSVGSD 177 Caenorhabditis ...
Q9XVM5       174 VSESLWFFDFAAVMEVVLVIAIIVNNVITYVMFRmkfkkkvvfnknaitpRQMQSSQEKQKRESGLDKMTFIVCFLELVY 253 Caenorhabditis ...
O45353       168 TTFVQWTSLTVMTSYFVTCVSIIIMYSQIAVVMVrark--------veqgVLTSTKTTKKLKDARLTLHVFILVLFCIVT 239 Caenorhabditis ...
Q9U316       182 KQMTSTFFKIGGSFLFLNCLYLIIAYFYLFYSLKkrnsri-----anfpvSKS--KQIQKLREIRLFIMISITVAVQLTI 254 Caenorhabditis ...
XP_002633578 173 KKMTTIFFTIGGGFLFSNCIYLIFSYCYLFVVLRkrntql-----sflstNVPKTKEKARKRERRLFTMCSIIVAVQMTI 247
Q86DM4       175 KQMTTIFFSIGGFFLFANYIYLITAYCFLFIILHkrnakl-----nslsiNVSKTKENDRKRERRLFIMCSVIVSVQMTI 249 Caenorhabditis ...
Q9U312       191 KSMTNTFFAIGGVFLFVNCVYLVATYCYLFWVIRkrqrinm---pptpviTNS--RSKAKMREARLFTMSTIIVGVQMCI 265 Caenorhabditis ...
Q9XU18       190 EDHVTYFFLIAGAILTVVCVYLIIAYSYLLAVLRknsnai-----kdsnmQKS--KTQIKKKEMKLFIMSSITVVIQVAA 262 Caenorhabditis ...
Q9U306       189 ENFIAVLFVIAGGFLATVCIYLIIAYCYLIFMLRkssnai-----kntqfHKS--RAVIKKKEVKLFFMSSITVAIQISI 261 Caenorhabditis ...
Q23041       177 KDFRRGFFMSAYVIETIFVASIMLINATMVIAFRtkykvr----lttqphLNQKVMNDKQRQEYNLNIVAALTCVAEIIY 252 Caenorhabditis ...
P92000       178 DTDADWFYNFVAIMEVVLVLAIIVNNVVTYTMFRlkfnkksaiksnsitpSQHQSNQEKQKRENGLDKMTFIVCLVELIY 257 Caenorhabditis ...
Q9XVM5       254 FAFVVYSLQINQTMNKR-TFYF--YYNILCVIYSTVSAWTLLIFSKPINLQVREKFSK 308 Caenorhabditis elegans
O45353       240 FFFYIGEYVLATDADNDrVRALrlFYPTLSGNLSFINPIMLLMMNRDVQSAFCCRFKV 297 Caenorhabditis elegans
Q9U316       255 LIFFSLKLLKFFELNME-EFYL--FYNALSDLFASINPYLLWIFSDSLRKYVYWKMGI 309 Caenorhabditis elegans
XP_002633578 248 LLFFILKVAKLFELTVD-EFYL--FYNLLSDLFASINPYLLWIFSDSLRKYVLTQLRL 302
Q86DM4       250 LIFFILKVAKVFELTLD-EFYV--LYNLLSDLFASINPYLLWIFSDSLRKYVLYQVGl 304 Caenorhabditis elegans
Q9U312       266 LILFIFKGADILAFTSD-QFYL--VYNAVSDLYASINPYLLWVFSDSLRKYILQRLGF 320 Caenorhabditis elegans
Q9XU18       263 LCLFASYAASILVISLD-KFYL--LYNAMSDLYAGINPYLLWIFSDSLRKYILIQLGL 317 Caenorhabditis elegans
Q9U306       262 LCLVIVYATSLLNFPLD-KFYL--FYNAISDLYAGINPYLLWIFSDSLRKHIWHRIGW 316 Caenorhabditis elegans
Q23041       253 YCYVIYVFGINTSVPTR-VFYL--LYDVINDLYCGISGWLLLIYSRSMKAHVTKMLRC 307 Caenorhabditis elegans
P92000       258 FAFVVYSLQINQYMNKR-IFYF--LYNILCVIYSTFSAWMLLIISKPINSQVRQNLGG 312 Caenorhabditis elegans
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