|
Name |
Accession |
Description |
Interval |
E-value |
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
5-395 |
0e+00 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 720.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 5 RMTPATACIHAN-PQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVAT 83
Cdd:TIGR01328 1 RMTFATRAIHAGyPPKDQFGALTPPIYQTSTFVFDSCEQGGNRFAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVAT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 84 SSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKI 163
Cdd:TIGR01328 81 SSGMGAIAATLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 164 IDMERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDITGS 243
Cdd:TIGR01328 161 IDMERVCRDAHSQ-GVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQIRMVGIKDMTGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 244 VISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGA 323
Cdd:TIGR01328 240 VISPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAGA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
1E5E_A 324 KKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:TIGR01328 320 KKLLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALDAL 391
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
9-393 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 603.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHANPQKD-QFGAAIPPIYQTSTFVFDncqqggnrFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:pfam01053 1 DTLAVHAGQRPDpQTGAVSVPIYLTSTYVFD--------FAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:pfam01053 73 AAITAAILALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIKDITGSVISP 247
Cdd:pfam01053 153 AIAKLAKKH-GILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGK-ELYFLQNATGAVLSP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 248 HDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLL 327
Cdd:pfam01053 231 FDAWLLLRGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFL 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
1E5E_A 328 DNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLD 393
Cdd:pfam01053 311 DNLKLFSLAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
6-395 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 591.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 6 MTPATACIHA-NPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATS 84
Cdd:COG0626 1 MGPATRAVHAgRDPDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 85 SGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKII 164
Cdd:COG0626 81 SGMAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 165 DMERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLL-QQIRMVGIkdITGS 243
Cdd:COG0626 161 DIAAIAAIAH-AAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELaERLRFLQN--ALGA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 244 VISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGA 323
Cdd:COG0626 238 VLSPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAA 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
1E5E_A 324 KKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:COG0626 318 RRFLDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
23-393 |
0e+00 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 581.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 23 GAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGD 102
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAADLFALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALLKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 103 HLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHSQeGVLVI 182
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEH-GALLV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 183 ADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKA-DLLQQIRMVGIkdITGSVISPHDAWLITRGLSTLN 261
Cdd:cd00614 160 VDNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGeALIQRLRFLRL--ALGTILSPFDAWLLLRGLKTLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 262 IRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGG 341
Cdd:cd00614 238 LRMERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGG 317
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
1E5E_A 342 CESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLD 393
Cdd:cd00614 318 VESLVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
4-397 |
0e+00 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 573.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 4 ERMTPATACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVA 82
Cdd:PRK06234 5 KKMGFATKAIHGGHIGDkQFGSLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 83 TSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLK 162
Cdd:PRK06234 85 AASGMGAISSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 163 IIDMERVCKDAHSQ-EGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDIT 241
Cdd:PRK06234 165 VTDIKAISNIAHENnKECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVKLFGIKDMT 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 242 GSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFE 321
Cdd:PRK06234 245 GSVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVE 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1E5E_A 322 GAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDALLR 397
Cdd:PRK06234 325 EGKVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALDLIVK 400
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
1-394 |
3.00e-167 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 475.29 E-value: 3.00e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 1 MAHERMTPATACIHANPQKDQ-FGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEA 79
Cdd:COG2873 1 MTEKKYGFETLALHAGQEPDPtTGARAVPIYQTTSYVFDDAEHAADLFALKEPGNIYTRIMNPTTDVLEKRIAALEGGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 80 CVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANP 159
Cdd:COG2873 81 ALATASGQAAITLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 160 TLKIIDMERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLI----------------- 222
Cdd:COG2873 161 ALDVLDIEAIAEIAHEH-GVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIvdggnfdwaangkfpel 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 223 ---------------CGKADLLQQIRMVGIKDiTGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKV 287
Cdd:COG2873 240 tepdpsyhglvyteaFGNAAFITKARVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 288 YYPGFEDHEGHDIAKKQM-RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAG 366
Cdd:COG2873 319 NYPGLPSHPYHELAQKYLpKGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAG 398
|
410 420
....*....|....*....|....*...
1E5E_A 367 ITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:COG2873 399 VTPDLIRLSVGIEDIDDIIADLDQALAA 426
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
1-397 |
1.34e-163 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 465.05 E-value: 1.34e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 1 MAHERMTPATACIHA--NPQKDQfGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTE 78
Cdd:PRK07503 3 DSHNNTGFSTRAIHHgyDPLDHG-GALVPPVYLTATFAFPTAEYGAECFAGEEEGHFYSRISNPTLALLEQRMASLEGGE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 79 ACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPAN 158
Cdd:PRK07503 82 AAVALASGMGAITATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 159 PTLKIIDMERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIK 238
Cdd:PRK07503 162 PNMRLVDIAAVAEIAH-GAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIRLEGLK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 239 DITGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKS 318
Cdd:PRK07503 241 DMTGAVMSPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKG 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
1E5E_A 319 GFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDALLR 397
Cdd:PRK07503 321 GIAAGRRFMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALDACAV 399
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
10-395 |
3.27e-156 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 445.82 E-value: 3.27e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 10 TACIHANPQKDQ-FGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMG 88
Cdd:PRK06767 8 TALIHHGYTSEEhKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAFGSGMA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 89 AIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMER 168
Cdd:PRK06767 88 AISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLIDLKQ 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 169 VCKDAhSQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDItGSVISPH 248
Cdd:PRK06767 168 VIRVA-KRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDI-GGIMAPF 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 249 DAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPgfedheGHDIAKKQMRMYGSMITFILKSGFEGAKKLLD 328
Cdd:PRK06767 246 DAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYP------EGELASRQMKRGGGVISFSIKGGKEETQAFIN 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
1E5E_A 329 NLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK06767 320 DLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
8-394 |
4.55e-150 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 430.19 E-value: 4.55e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK08133 7 FDTLAVRAGQLRSPFGEHSEALFLTSSFVFESAAEAAARFAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATASGM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:PRK08133 87 AAILAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELADIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIrmVGIKDITGSVISP 247
Cdd:PRK08133 167 ALAEIAHAA-GALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEV--FGFLRTAGPTLSP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 248 HDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLL 327
Cdd:PRK08133 244 FNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAWRVI 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
1E5E_A 328 DNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK08133 324 DATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLAA 390
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
1-394 |
1.05e-138 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 401.33 E-value: 1.05e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 1 MAHERMTPATACIHANPQKDQF-GAAIPPIYQTSTFVFDNCqqGGNRfagqeSGYIYTRLGNPTVSNLEGKIAFLEKTEA 79
Cdd:PRK07811 6 DHHANQGFATRAIHAGYEPDPAtGAVNPPIYASSTFAQDGV--GGLR-----GGYEYARTGNPTRTALEEQLAALEGGAY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 80 CVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANP 159
Cdd:PRK07811 79 GRAFSSGMAATDCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 160 TLKIIDMERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG-LICGKADLLQQIRMvgIK 238
Cdd:PRK07811 159 LLSITDIAALAELAHDA-GAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGaLVTNDEELDEAFAF--LQ 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 239 DITGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKS 318
Cdd:PRK07811 236 NGAGAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAG 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
1E5E_A 319 GFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREaagITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK07811 316 GEEAARDFCARTKVFTLAESLGGVESLIEHPSAMTHASTAGSQLE---VPDDLVRLSVGIEDVADLLADLEQALGQ 388
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
6-393 |
1.19e-134 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 390.62 E-value: 1.19e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 6 MTPATACIHANPQKD-QFGAAIPPIYQTSTFvfdncQQGGnrfAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATS 84
Cdd:PRK07671 1 MRAKTKLIHGGIIGDpSTGAVSVPIYQVSTY-----KQEA---VGKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 85 SGMGAIAAtVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKII 164
Cdd:PRK07671 73 SGMAAITA-VMMLFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKIT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 165 DMERVCKDAhSQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIKDITGSV 244
Cdd:PRK07671 152 DIKKISTIA-KEKGLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAE-DLHFVQNSTGGI 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 245 ISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGfEGAK 324
Cdd:PRK07671 230 LGPQDSWLLLRGLKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDVGSE-ETAN 308
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
1E5E_A 325 KLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLD 393
Cdd:PRK07671 309 KVLERLQYFTLAESLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
8-392 |
9.46e-134 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 389.80 E-value: 9.46e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSG 86
Cdd:TIGR01326 2 FETLQLHAGQEPDpTTGSRAVPIYQTTSYVFDSTEHAAALFGLQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAVASG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 87 MGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDM 166
Cdd:TIGR01326 82 QAAITYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 167 ERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC----------------------- 223
Cdd:TIGR01326 162 EAIAEVAHRH-GIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVdggkfdwnngrfplfttpdpsyh 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 224 --------GKADLLQQIRMVGIKDiTGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDH 295
Cdd:TIGR01326 241 glvftetlGNPAFILKARVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 296 EGHDIAKKQM-RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRL 374
Cdd:TIGR01326 320 PHHALAKKYLpKGFGAVLSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRL 399
|
410
....*....|....*...
1E5E_A 375 SVGIEDADELIADFKQGL 392
Cdd:TIGR01326 400 SVGIENIDDIIADLEQAL 417
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
22-395 |
1.32e-130 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 381.01 E-value: 1.32e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 22 FGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAATVLTILKAG 101
Cdd:PRK08249 24 YGATQVPVVLSVAYGYDDIDEWYDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTFLKPG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 102 DHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHsQEGVLV 181
Cdd:PRK08249 104 DRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAK-KVGALV 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 182 IADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMvgIKDITGSVISPHDAWLITRGLSTLN 261
Cdd:PRK08249 183 VVDNTFATPINQNPLALGADLVIHSATKFLSGHADALGGVVCGSKELMEQVYH--YREINGATMDPMSAYLILRGMKTLK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 262 IRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGG 341
Cdd:PRK08249 261 LRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKRLLPKLRYAHRAANLGA 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
1E5E_A 342 CESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK08249 341 VETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHL 394
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
1-395 |
5.69e-129 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 376.42 E-value: 5.69e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 1 MAHErMTPATACIHANPQKD-QFGAAIPPIYQTSTFvfdncqqggNRFAGQESG-YIYTRLGNPTVSNLEGKIAFLEKTE 78
Cdd:PRK08064 1 MAMS-YSIDTLLLHNQYKHDkQTGAVNVPIYHASTF---------HQFDFDTFGkYDYSRSGNPTREALEDIIAELEGGT 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 79 ACVATSSGMGAIAATVLTILKaGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPAN 158
Cdd:PRK08064 71 KGFAFASGMAAISTAFLLLSK-GDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSN 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 159 PTLKIIDMERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIK 238
Cdd:PRK08064 150 PLLKVTDIRGVVKLAKAI-GCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQ-KLYFLQ 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 239 DITGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKS 318
Cdd:PRK08064 228 NSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQS 307
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
1E5E_A 319 GfEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK08064 308 E-EAVRQFVSHVKLPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYV 383
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
6-395 |
2.78e-125 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 366.92 E-value: 2.78e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 6 MTPATACIHANPQKDQF-GAAIPPIYQTSTFvfdncQQGGnrfAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATS 84
Cdd:PRK06176 1 MRMQTKLIHGGISEDTTtGAVSVPIYQTSTY-----RQDA---IGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 85 SGMGAIAAtVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKII 164
Cdd:PRK06176 73 SGLAGIHA-VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKIT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 165 DMERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIKDITGSV 244
Cdd:PRK06176 152 DLAQCASVAKDH-GLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQ-EIAFFQNAIGGV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 245 ISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGfEGAK 324
Cdd:PRK06176 230 LGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKND-SEAV 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1E5E_A 325 KLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK06176 309 AFVESLKLFILGESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKI 379
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
8-394 |
8.65e-120 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 352.95 E-value: 8.65e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKD-QFGAAIPPIYQTSTFVFDNcqqggnrfAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSG 86
Cdd:TIGR02080 4 QATIAVRSGLNSDtQYGCVVPPIYLSTTYNFTG--------FNEPRAYDYSRSGNPTRDLLQQALAELEGGAGAVVTNTG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 87 MGAIAATVLTILKAGDHLISDECLYGCTHALFEhALTKFG-IQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIID 165
Cdd:TIGR02080 76 MSAIHLVTTALLGPDDLLVAPHDCYGGTYRLLN-ALAKKGcFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 166 MERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG-LICGKADLLQQIRMVGikDITGSV 244
Cdd:TIGR02080 155 IAKICHLAKAV-GAVVVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVIAGaVIAKDPQVAEELAWWA--NNLGVT 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 245 ISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAK 324
Cdd:TIGR02080 232 GGAFDSYLTLRGLRTLVARMRLQQRNAQAIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGEQTVR 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 325 KLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:TIGR02080 312 RFLGGLSLFTLAESLGGVESLIAHPATMTHAAMGPEARAEAGISDTLLRLSVGLEDADDLIADLEQGLRA 381
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
23-394 |
4.17e-118 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 350.13 E-value: 4.17e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 23 GAAIPPIYQTSTFVFDNCQQGGNRF----------AGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAA 92
Cdd:PRK07049 34 GAVKPPVFLTSTFVFRSAEDGRDFFdyvsgrkeppAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIAT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 93 TVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQ-VDFINTAIPGEVKKHM-----KPNTKIVYFETPANPTLKIIDM 166
Cdd:PRK07049 114 TLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaaKGRVSLILIETPANPTNSLVDV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 167 E---RVCKDAHSQEG--VLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRmvGIKDIT 241
Cdd:PRK07049 194 AavrRVADAIEARQGhrPIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAVLGRKALIRQVR--ALRSAI 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 242 GSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGF--EDHEGHDIAKKQMRMYGSMITFILKSG 319
Cdd:PRK07049 272 GTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGAVYKRQCTGAGSTFSFDIKGG 351
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
1E5E_A 320 FEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK07049 352 QAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQALDA 426
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
8-392 |
6.21e-118 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 347.97 E-value: 6.21e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKDQFGAAIPPIYQTSTFVFDNcqqggnrfAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:TIGR01329 1 LSTLLVNTDNKNDPYDASSMPIYQTATFKQPL--------AIENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAaTVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:TIGR01329 73 AALD-VITRLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIKDITGSVISP 247
Cdd:TIGR01329 152 KISEMAHAQ-NALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAK-KVYFLQNSTGSGLAP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 248 HDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSgFEGAKKLL 327
Cdd:TIGR01329 230 FDCWLLLRGIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFETGS-VALSKRLV 308
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
1E5E_A 328 DNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGL 392
Cdd:TIGR01329 309 EATKLFSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
6-395 |
2.07e-117 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 347.05 E-value: 2.07e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 6 MTPATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRfaGQEsgYIYTRLGNPTVSNLEGKIAFLEKTEACVATSS 85
Cdd:PRK08574 1 MRRGTDAVRGYRGSDPYGSLQPPIYLTALFRQEGEAYPSDR--GFD--LKYSREENPTLRPLEEALAKLEGGVDALAFNS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 86 GMGAIAATVLTILKAGDHLISDECLYGCTHALFEhALTKFGIQV--------DFINTAipgevkkhMKPNTKIVYFETPA 157
Cdd:PRK08574 77 GMAAISTLFFSLLKAGDRVVLPMEAYGTTLRLLK-SLEKFGVKVvlaypsteDIIEAI--------KEGRTKLVFIETMT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 158 NPTLKIIDMERVCKDAhSQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKA-----DLLQQI 232
Cdd:PRK08574 148 NPTLKVIDVPEVAKAA-KELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSgefleELWEWR 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 233 RMVGikditgSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMR--MYGS 310
Cdd:PRK08574 227 RRLG------TIMQPFEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRLFGkdLYGG 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 311 MITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQ 390
Cdd:PRK08574 301 VVSFRVKGGRDAVLKFLRSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQ 380
|
....*
1E5E_A 391 GLDAL 395
Cdd:PRK08574 381 ALGSI 385
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
20-395 |
2.89e-113 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 336.03 E-value: 2.89e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 20 DQFGAAIPPIYQTSTFVFdncqQGGNRFAgqesgyiYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAATVLTILK 99
Cdd:PRK06460 14 EATGAITTPIYQTTAYHY----PEGEKYR-------YSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 100 AGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKdAHSQEGV 179
Cdd:PRK06460 83 PGNSVLVHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSK-VCKENGS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 180 LVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMvgIKDITGSVISPHDAWLITRGLST 259
Cdd:PRK06460 162 ILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGKLLNVIDQ--MRRTLGTSLDPHAAYLTLRGIKT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 260 LNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLLDNLKLITLAVSL 339
Cdd:PRK06460 240 LKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIPAQTL 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
1E5E_A 340 GGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK06460 320 GGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRALSTL 375
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
8-394 |
3.00e-111 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 331.72 E-value: 3.00e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK07504 11 PATRLVHSGTLRSQFGETSEALFLTQGFVYDTAEAAEARFKGEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:PRK07504 91 AAVTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLI-CGKADLLQQIRMVGIKdiTGSVIS 246
Cdd:PRK07504 171 AVAKIAN-QAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVlSDKAWIEEHLQDYFRH--TGPSLS 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 247 PHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKL 326
Cdd:PRK07504 248 PFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRF 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
1E5E_A 327 LDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK07504 328 LNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALKK 395
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
1-394 |
5.59e-110 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 329.50 E-value: 5.59e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 1 MAHER-MTPATACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTE 78
Cdd:PRK08248 1 MSEERtFRLETLAIHAGQEIDpTTGSRAVPIYQTTSYGFRDSEHAANLFSLKEFGNIYTRIMNPTTDVFEKRIAALEGGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 79 ACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPAN 158
Cdd:PRK08248 81 GALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 159 PTLKIIDMERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC--------------- 223
Cdd:PRK08248 161 PKGDVLDIEAVAAIAH-EHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsgkfpg 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 224 -----------------GKADLLQQIRMVGIKDItGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEK 286
Cdd:PRK08248 240 ltepdpsyhglvytdavGEAAYITKARVQLLRDL-GAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEW 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 287 VYYPGFEDHEGHDIAKKQM-RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAA 365
Cdd:PRK08248 319 VSYPGLPSHPSYELAKKYLpKGQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAA 398
|
410 420
....*....|....*....|....*....
1E5E_A 366 GITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK08248 399 GVTPGLVRLSVGTEAIDDILDDLRQAIRQ 427
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
7-392 |
1.03e-108 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 325.54 E-value: 1.03e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 7 TPATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSG 86
Cdd:PRK07810 15 SQATIGVRGGLLRSGFEETAEALYLTSGYVYESAAAAEAAFTGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 87 MGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDM 166
Cdd:PRK07810 95 MSAVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 167 ERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLL-----QQIRMvgikdiT 241
Cdd:PRK07810 175 AAVSELAHAA-GAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIdgpvqKLMRH------T 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 242 GSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFE 321
Cdd:PRK07810 248 GPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPED 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
1E5E_A 322 GAKK----LLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGL 392
Cdd:PRK07810 328 AAKKrafeVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
10-394 |
2.05e-108 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 324.16 E-value: 2.05e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 10 TACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMG 88
Cdd:PRK06434 11 TRAVQSGELRDpRFGNVTTPIFETSTFVYPNSEKEAYMDSTRGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 89 AIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKkhMKP-NTKIVYFETPANPTLKIIDME 167
Cdd:PRK06434 91 AITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLD--FDPsNYDLIYAESITNPTLKVPDIK 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHsqeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGlICGKADLLQQIRMVGIKDITGSVISP 247
Cdd:PRK06434 169 NVSSFCH---ENDVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMG-VAGTNNKSIFNNLVERRKTLGSNPDP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 248 HDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEdheghdIAKKQMRMYGSMITFILKSgFEGAKKLL 327
Cdd:PRK06434 245 IQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDTE------IGKKVLRGFGGMLSFELRS-MEDVHKFI 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
1E5E_A 328 DNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK06434 318 RNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
23-395 |
4.30e-108 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 322.42 E-value: 4.30e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 23 GAAIPPIYQTSTFvfdncqqgGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAaTVLTILKAGD 102
Cdd:PRK08247 21 GTVNPPVYFSTAY--------RHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQ-LVMSLFRSGD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 103 HLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAhSQEGVLVI 182
Cdd:PRK08247 92 ELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKIA-KKHGLLLI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 183 ADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIKDITGSVISPHDAWLITRGLSTLNI 262
Cdd:PRK08247 171 VDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCE-RLAYYQNAAGAVLSPFDSWLLIRGMKTLAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 263 RMKAESENAMKVAEYLKSHPAVEKVYYPGfedheghdiakkqmrmYGSMITFILKSGfEGAKKLLDNLKLITLAVSLGGC 342
Cdd:PRK08247 250 RMRQHEENAKAIAAFLNEQPGVTDVLYPG----------------RGGMLSFRLQDE-EWVNPFLKSLKLITFAESLGGV 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
1E5E_A 343 ESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK08247 313 ESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAFKQV 365
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
10-394 |
8.55e-108 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 324.01 E-value: 8.55e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 10 TACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMG 88
Cdd:PRK07812 16 TKQIHAGQTPDpATNARALPIYQTTSYTFDDTDHAAALFGLAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 89 AIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFI-NTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:PRK07812 96 AETFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLDIP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC--GKADLLQ--------------- 230
Cdd:PRK07812 176 GVAEVAH-EAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdgGTFDWTQgrfpgfttpdpsyhg 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 231 -------------QIRMVGIKDiTGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEG 297
Cdd:PRK07812 255 vvfaelgppayalKARVQLLRD-LGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPW 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 298 HDIAKKQM-RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSV 376
Cdd:PRK07812 334 YERAKRLApKGTGAVLSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAV 413
|
410
....*....|....*...
1E5E_A 377 GIEDADELIADFKQGLDA 394
Cdd:PRK07812 414 GIEGIDDILADLEAGFAA 431
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
9-392 |
2.23e-107 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 321.94 E-value: 2.23e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHANPQKDQ-FGAAIPPIYQTSTFVFDncqqggnRFaGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK08776 14 ATAAVRAGIDRDTaYGAVTPPIVLSSNFSFD-------GF-GNKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITATGM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEhALTKFG----IQVDFINtaiPGEVKKHMKPNTKIVYFETPANPTLKI 163
Cdd:PRK08776 86 GAINLVLNALLQPGDTLVVPHDAYGGSWRLFN-ALAKKGhfalITADLTD---PRSLADALAQSPKLVLIETPSNPLLRI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 164 IDMERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG-LICGKADLLQQirMVGIKDITG 242
Cdd:PRK08776 162 TDLRFVIEAAH-KVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGaVVARDAELHQQ--LVWWANALG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 243 SVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEG 322
Cdd:PRK08776 239 LTGSPFDAFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAA 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 323 AKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGL 392
Cdd:PRK08776 319 VRAFVDGLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
9-395 |
1.01e-105 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 318.58 E-value: 1.01e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK05994 9 ATLAVHAGAQPDpTTGARATPIYQTTSFVFNDADHAASLFGLQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVASGH 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:PRK05994 89 AAQFLVFHTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTDIA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLI--CGKAD--------LLQQ------ 231
Cdd:PRK05994 169 AIAEVAH-RAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIvdGGTFDwsksgkypMLSEprpeyh 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 232 ----------------IRMVGIKDItGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDH 295
Cdd:PRK05994 248 glvlhetfgnfafaiaARVLGLRDL-GPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDD 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 296 EGHDIAKKQM-RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRL 374
Cdd:PRK05994 327 PYHALAQKYSpKGAGAVFTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRL 406
|
410 420
....*....|....*....|.
1E5E_A 375 SVGIEDADELIADFKQGLDAL 395
Cdd:PRK05994 407 SIGIEDVDDIIADLEQALAKA 427
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
10-394 |
1.83e-105 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 318.22 E-value: 1.83e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 10 TACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMG 88
Cdd:PRK08134 11 TLALHAGAAPDpATGARAVPIHLTTSFVFRDSDHAAALFNLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 89 AIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMER 168
Cdd:PRK08134 91 ALHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIPT 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 169 VCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC------------------------- 223
Cdd:PRK08134 171 VAAIAH-EAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVdggrfdweasgkfpeltepyagfhg 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 224 -------GKADLLQQIRMVGIKDItGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHE 296
Cdd:PRK08134 250 mvfaeesTVAAFLLRARREGLRDF-GACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 297 GHDIAKKQM-RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLS 375
Cdd:PRK08134 329 DHALAKRLLpRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLS 408
|
410
....*....|....*....
1E5E_A 376 VGIEDADELIADFKQGLDA 394
Cdd:PRK08134 409 IGLEDADDLIDDLKRALKA 427
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
9-398 |
9.93e-103 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 312.35 E-value: 9.93e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHANPQKDQFGAAIPPIYQTSTFvfdncqqggNRFAGQESG-YIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PLN02509 88 STLLVNLDNKFDPFDAMSTPLYQTATF---------KQPSAIENGpYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGM 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAAtVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:PLN02509 159 AALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIR 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQiRMVGIKDITGSVISP 247
Cdd:PLN02509 238 KIAEMAHAQ-GALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEGSGLAP 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 248 HDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSgFEGAKKLL 327
Cdd:PLN02509 316 FDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGS-VALSKHLV 394
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1E5E_A 328 DNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADfkqgLDALLRS 398
Cdd:PLN02509 395 ETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISD----LDIAFRT 461
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
6-397 |
5.77e-102 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 307.59 E-value: 5.77e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 6 MT--PATACIHANPQKD-QFGAAIPPIYQTSTFVFDNCQQggnrfagqESGYIYTRLGNPTVSNLEGKIAFLEKTEACVA 82
Cdd:PRK08045 1 MTrkQATIAVRSGLNDDeQYGCVVPPIHLSSTYNFTGFNE--------PRAHDYSRRGNPTRDVVQRALAELEGGAGAVL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 83 TSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEhALTKFG-IQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTL 161
Cdd:PRK08045 73 TNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFD-SLAKRGcYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 162 KIIDMERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGK-ADLLQQI----RMVG 236
Cdd:PRK08045 152 RVVDIAKICHLAR-EAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKdPDVVTELawwaNNIG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 237 IkdiTGSVIsphDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFIL 316
Cdd:PRK08045 231 V---TGGAF---DSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFEL 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 317 KSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDALL 396
Cdd:PRK08045 305 DGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAAN 384
|
.
1E5E_A 397 R 397
Cdd:PRK08045 385 K 385
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
8-397 |
1.99e-101 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 306.24 E-value: 1.99e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK05968 9 DLAALITAHDEGNAFDAVVPPIFQTSLFTFDSYDEMEDVYAGEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMkPNTKIVYFETPANPTLKIIDME 167
Cdd:PRK05968 89 AAISSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESPTSWVFELQDVA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAhSQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRmVGIKDITGSVISP 247
Cdd:PRK05968 168 ALAALA-KRHGVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARIN-AEAYPYLGAKLSP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 248 HDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHeghdiAKKQMRMYGSMITFILKSGFEgAKKLL 327
Cdd:PRK05968 246 FEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANH-----PPAGLSGTSGLFSFIFREGID-VRAFA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1E5E_A 328 DNLKLITLAVSLGGCESLIQhPASMTHAVVPKEEREAA-GITDGMIRLSVGIEDADELIADFKQGLDALLR 397
Cdd:PRK05968 320 DALKLFRLGVSWGGHESLVV-PAEVVLQQKAQPNSAARfGVSPRSVRLHVGLEGTEALWADLEQALAAASR 389
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
8-390 |
7.77e-98 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 297.19 E-value: 7.77e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKD-QFGAAIPPIYQTSTFVFDNcqqggnrfAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSG 86
Cdd:PRK08861 6 PATIAVRTGIESDsQYHAVVPPIYLSTNYGFPA--------FGEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVTNCG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 87 MGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDM 166
Cdd:PRK08861 78 TSALNLWVSALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 167 ERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG-LICGKADLLQQIRMVGikDITGSVI 245
Cdd:PRK08861 158 AELCQKAK-AVGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGvLITKTKEHAEELAWWG--NCIGATG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 246 SPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKK 325
Cdd:PRK08861 235 TPFDSYMTLRGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKV 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
1E5E_A 326 LLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQ 390
Cdd:PRK08861 315 FVKALALFSLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQ 379
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
18-395 |
2.22e-97 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 296.21 E-value: 2.22e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 18 QKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAATVLTI 97
Cdd:PRK05939 3 AGIEHGAVHKPIHTSVTYGYEDARDLIDVFQGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 98 LKAGDHLISDECLYGCTHALFEhALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMER---VCKdah 174
Cdd:PRK05939 83 LRAGDHLVSSQFLFGNTNSLFG-TLRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGigaLCR--- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 175 sQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICG-----------------KADL----LQQIR 233
Cdd:PRK05939 159 -ERGLLYVVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTDtglfdwsaypnifpayrKGDPqqwgLTQIR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 234 MVGIKDItGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMIT 313
Cdd:PRK05939 238 KKGLRDM-GATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLS 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 314 FILKSGfEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLD 393
Cdd:PRK05939 317 FELADG-IDCFDFLNRLKLVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALD 395
|
..
1E5E_A 394 AL 395
Cdd:PRK05939 396 AT 397
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
6-394 |
6.75e-95 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 290.65 E-value: 6.75e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 6 MTPATACIHANPQKDQFGAAIP-PIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATS 84
Cdd:PRK06084 1 MKLETLAIHAGYSPDPTTKAVAvPIYQTTSYAFDDTQHGADLFDLKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 85 SGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKII 164
Cdd:PRK06084 81 SGMAAITYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 165 DMERVCKDAHsQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC--------------------- 223
Cdd:PRK06084 161 DIQALADAAH-RHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVdsgkfpwaehkerfallntpd 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 224 ------------GKADLLQQIRMVGIKDiTGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPG 291
Cdd:PRK06084 240 psyhgvtyteafGPAAFIGRCRVVPLRN-MGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 292 FEDHEGHDIAKKQMR-MYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDG 370
Cdd:PRK06084 319 LPDHPEHELARRYMGgKPASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRD 398
|
410 420
....*....|....*....|....
1E5E_A 371 MIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK06084 399 MVRLSIGIEHIDDIIADLAQALDA 422
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
9-395 |
3.16e-92 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 284.46 E-value: 3.16e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHA-NPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK05613 15 ETRSIHAgQSVDSDTSARNLPIYQTTSYVFDSAEHAKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFASGQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFI-NTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDM 166
Cdd:PRK05613 95 AAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADVLDI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 167 ERVCKDAHSQEgVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC--GKADLLQQ------------- 231
Cdd:PRK05613 175 PAVAEVAHRNQ-VPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdgGKFDWTVErdgkpvfpyfvtp 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 232 ------------------IRM-VGIKDITGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGF 292
Cdd:PRK05613 254 dpayhglkyadlgapafgLKArAGLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAGL 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 293 EDHEGHDIAKKQMRMY-GSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGM 371
Cdd:PRK05613 334 KDSPWYATKEKLGLKYtGSVLSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQAT 413
|
410 420
....*....|....*....|....
1E5E_A 372 IRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK05613 414 VRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
8-395 |
7.53e-88 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 270.71 E-value: 7.53e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHAN-PQKDQFGAAIPPIYQTSTFVFDncqqggnrfAGQESG-YIYTRLGNPTVSNLEGKIAFLEKTEaCVATSS 85
Cdd:PRK07582 4 DGTRSVHAGgPEAVPGEPVLPGPVFAAPYHLS---------PGEPTGpDTYGRASNPTWRALEAALGELEGAE-ALVFPS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 86 GMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEvkkHMKPNTKIVYFETPANPTLKIID 165
Cdd:PRK07582 74 GMAAITAVLRALLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREAPTAGMAE---AALAGADLVLAETPSNPGLDVCD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 166 MERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGK-ADLLQQIRMVgiKDITGSV 244
Cdd:PRK07582 151 LAALAAAAHAA-GALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRdPELMAAVERW--RLLAGAI 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 245 ISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGfEGAK 324
Cdd:PRK07582 228 PGPFEAWLAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFELADA-AAAE 306
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
1E5E_A 325 KLLDNLKLITLAVSLGGcesliqhpasmTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK07582 307 RFVAASRLVVAATSFGG-----------VHTSADRRARWGDAVPEGFVRLSCGIEDTDDLVADLERALDAL 366
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
8-397 |
6.83e-86 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 267.40 E-value: 6.83e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 8 PATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQ---ESG-YIYTRLGNPTVSNLEGKIAFLEKTEACVAT 83
Cdd:PLN02242 18 PAAALASARHEFGEHGGVNMSIEASATFTVMEPDTMRRMFSGElgpDRDfYIYSRHFNPTVLNLGRQMAALEGTEAAYCT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 84 SSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHAL-TKFGIQVDFINTAIPGEVKKHMKPN-TKIVYFETPANPTL 161
Cdd:PLN02242 98 ASGMSAISSVLLQLCSSGGHVVASNTLYGGTHALLAHFLpRKCNITTTFVDITDLEAVKKAVVPGkTKVLYFESISNPTL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 162 KIIDMERVCKDAHSQeGVLVIADNTFcSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQirMVGIKD-- 239
Cdd:PLN02242 178 TVADIPELARIAHEK-GVTVVVDNTF-APMVLSPARLGADVVVHSISKFISGGADIIAGAVCGPAELVNS--MMDLHHga 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 240 --ITGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAveKVYYPGFEDHEGHDIAKKQMRM---YGSMITF 314
Cdd:PLN02242 254 lmLLGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELGL--KVIYPGLEDHPQHALLKSMANKgygFGGLLCL 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 315 ILKSGfEGAKKLLDNLKLIT----LAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADEliADFKQ 390
Cdd:PLN02242 332 DMDTE-ERANRLMRYLQNSTqfgfMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVGYTGTLE--QRWSQ 408
|
....*..
1E5E_A 391 GLDALLR 397
Cdd:PLN02242 409 FEKALSA 415
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
9-394 |
5.76e-85 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 263.22 E-value: 5.76e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHANPQKDQ-FGAAIPPIYQTSTFVFDNcqqggnrfAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGM 87
Cdd:PRK07269 8 NTILAQAGIKSDEaTGALVTPLHFSTTYQHPE--------FGQSTGFDYTRTKNPTRAKLEETLAAIESADYALATSSGM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 88 GAIAaTVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAipGEVKKHMKPNTKIVYFETPANPTLKIIDME 167
Cdd:PRK07269 80 SAIV-LAFSVFPVGSKVVAVRDLYGGSFRWFNQQEKEGRFHFTYANTE--EELIAAIEEDTDIVYIETPTNPLMVEFDIE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 168 RVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG-LICGKADLLQqiRMVGIKDITGSVIS 246
Cdd:PRK07269 157 KVAKLAHAK-GAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGvVVTNDLELYE--KLFYNLNTTGAVLS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 247 PHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGfedheghdiakkqmrmYGSMITFILKSGfEGAKKL 326
Cdd:PRK07269 234 PFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTG----------------KGGMISFKVADE-TRIPHI 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
1E5E_A 327 LDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK07269 297 LNSLKVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALEG 364
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
4-392 |
1.59e-75 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 241.11 E-value: 1.59e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 4 ERMTPATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVAT 83
Cdd:PRK06702 3 ESWGKGTICVQGGYTPKNGEPRVLPLYQSTTYKYDTSDDLAALFNLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVAT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 84 SSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPG-EVKKHMKPNTKIVYFETPANPTLK 162
Cdd:PRK06702 83 ASGQAAIMLAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNLTAdEIVALANDKTKLVYAESLGNPAMN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 163 IIDMERVcKDAHSQEGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLIC------------------- 223
Cdd:PRK06702 163 VLNFKEF-SDAAKELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelvepd 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 224 ------------GKADLLQQIRMVGIKDItGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPG 291
Cdd:PRK06702 242 psyhgvsyvqnfGAAAYIVKARVQLLRDY-GNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 292 FEDHEGHDIAKKQMRMYGS-MITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAGITDG 370
Cdd:PRK06702 321 LDSNENYSLAQKYLKKGASgVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSD 400
|
410 420
....*....|....*....|..
1E5E_A 371 MIRLSVGIEDADELIADFKQGL 392
Cdd:PRK06702 401 LIRLSVGIEDVSDIIADLEAAL 422
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
16-394 |
5.22e-72 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 230.85 E-value: 5.22e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 16 NPQKDQFGAAIPPIYQTSTFVFDNCQQggnrFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAATVL 95
Cdd:PRK05967 22 NDPGDYHGFVNPPVVHASTVLFPDAET----MATRGQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVPFL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 96 TILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHS 175
Cdd:PRK05967 98 GFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEAAHR 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 176 QeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKdiTGSVISPHDAWLITR 255
Cdd:PRK05967 178 H-GAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEKCWPQLLEAHGT--LGLCAGPDDTYQILR 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 256 GLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKK----LLDNLK 331
Cdd:PRK05967 255 GLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPEKGKAkahaFLDALE 334
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
1E5E_A 332 LITLAVSLGGCESLIQHpASMTHAVVPKeereaaGITDG-MIRLSVGIEDADELIADFKQGLDA 394
Cdd:PRK05967 335 IFGLGYSWGGYESLALH-VKLGDRTVAK------APYAGpVIRLQIGLEDVPDLKADLERGFAA 391
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
27-393 |
5.06e-70 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 225.77 E-value: 5.06e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 27 PPIYQTSTFVFDNCQQGGNRFAGQESGYI-YTRLGNPTVSNLEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGDHLI 105
Cdd:PRK09028 25 PPVFRASTVVFDTVAEMRHAAKNRANGEMfYGRRGTPTHFAFQAAIVELEGGAGTALYPSGAAAISNALLSFLKAGDHLL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 106 SDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHsQEGVLVIADN 185
Cdd:PRK09028 105 MVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQDVPTLSRIAH-EHDIVVMLDN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 186 TFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIkdITGSVISPHDAWLITRGLSTLNIRMK 265
Cdd:PRK09028 184 TWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATANEKHWDQLREHSY--LMGQCTSPDDVYLAMRGLRTLGVRLA 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 266 AESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGA-KKLLDNLKLITLAVSLGGCES 344
Cdd:PRK09028 262 QHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKQGDPKAvTALVEGMQHFKMGFSWGGFES 341
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
1E5E_A 345 LIQHPASMTH---AVVPKEEREaagitdgMIRLSVGIEDADELIADFKQGLD 393
Cdd:PRK09028 342 LILGVFGINKlrtATNWDFSKP-------LIRLHIGLEDVDDLIADLEAGFE 386
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
10-395 |
2.18e-68 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 220.90 E-value: 2.18e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 10 TACIHANPQK-DQFGAAIPPIYQTSTFVFDNcqQGGNRFAGQEsgYIYTRLGNPTVSNLEGKIAFLEKTEACVATSSGMG 88
Cdd:TIGR01324 1 TRLIHSGRQPrFSQGSVNPPLQRASTVLFDS--HAAQRRAKGE--LTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 89 AIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMER 168
Cdd:TIGR01324 77 AVTNSILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 169 VCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIkdITGSVISPH 248
Cdd:TIGR01324 157 IAKAARNP-GIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVANARTWDQLREHSY--LMGQMVDAD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 249 DAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGF-EGAKKLL 327
Cdd:TIGR01324 234 DAYTTLRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRLTqKQVHAFL 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
1E5E_A 328 DNLKLITLAVSLGGCESLI-QHPASMTHAVVPKEEREAAgitdgMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:TIGR01324 314 DHLQLFGLGYSWGGYESLAlCNQPELGHRPNIKRNLEGP-----LIRVHIGLENVDDLKADLKAGFEAI 377
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
5-397 |
7.16e-62 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 204.57 E-value: 7.16e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 5 RMTPATACIHANPQ-KDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSNLEGKIAFLEKTEACVAT 83
Cdd:PRK07050 7 KRALQTRIVQPDDQiPPGFRSFVTPVARASTVVFPDLATMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 84 SSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKI 163
Cdd:PRK07050 87 PSGLAAISLVYFGLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 164 IDMERVCKDAHSQeGVLVIADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG-LICGKADL---LQQIRMVgikd 239
Cdd:PRK07050 167 PDVPAITAAARAR-GVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGaTITADAELhakLKLARMR---- 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 240 iTGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSG 319
Cdd:PRK07050 242 -LGIGVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDER 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 320 FEGAK--KLLDNLKLITLAVSLGGCESL--IQHPASMTHAVVPKEEReaagitdgMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK07050 321 YSPAQvdAFVEALELFAIGWSWGGACSLamPYDVASMRTAKWPHRGT--------LVRLYIGLEDEADLIADLEQALEAA 392
|
..
1E5E_A 396 LR 397
Cdd:PRK07050 393 LA 394
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
9-395 |
5.72e-58 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 194.15 E-value: 5.72e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 9 ATACIHANPQKDQFGAAIPPIYQ-TSTFVFDNCQQGGNRFAGQESGYI-YTRLGNPTVSNLEGKIAFLEKTEACVATSSG 86
Cdd:PRK08114 7 DTQLVNAGRSKKYTQGSVNSVIQrASSLVFDSVEAKKHATRNRANGELfYGRRGTLTHFSLQEAMCELEGGAGCALYPCG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 87 MGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDM 166
Cdd:PRK08114 87 AAAVANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITMEVHDV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 167 ERVCKDAHSQ--EGVLVIaDNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIR-----Mvgikd 239
Cdd:PRK08114 167 PAIVAAVRSVnpDAVIMI-DNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVANARCWEQLRensylM----- 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 240 itGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSG 319
Cdd:PRK08114 241 --GQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 320 FEGAK--KLLDNLKLITLAVSLGGCESLI--QHPASMThAVVPKEEREAAGItdgMIRLSVGIEDADELIADFKQGLDAL 395
Cdd:PRK08114 319 LTDEQlaNYLDNFSLFSMAYSWGGFESLIlaNQPEEIA-AIRPAGEVDFTGT---LIRLHIGLEDVDDLIADLAAGFARI 394
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
73-225 |
4.83e-12 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 63.94 E-value: 4.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 73 FLEKTEACVATSSGMGAIAATVLTILKAGDHLISDEclyGCTHALFEHALTKFGIQV----------DFINTAIPGEVKK 142
Cdd:cd01494 13 LQPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDA---NGHGSRYWVAAELAGAKPvpvpvddagyGGLDVAILEELKA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 143 hmKPNTKIVYFETPANPTLKIIDMERVCKDAHSQeGVLVIADNTFCSPMITNPV----DFGVDVVVHSATKYINGhtdVV 218
Cdd:cd01494 90 --KPNVALIVITPNTTSGGVLVPLKEIRKIAKEY-GILLLVDAASAGGASPAPGvlipEGGADVVTFSLHKNLGG---EG 163
|
....*..
1E5E_A 219 AGLICGK 225
Cdd:cd01494 164 GGVVIVK 170
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
81-291 |
4.38e-08 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 54.65 E-value: 4.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 81 VATSSGMGAIAATVLTILKAGDH-LISDEclygcTHALFEHALTKFGIQVDFINTAIPG-------EVKKHMKPNTKIVY 152
Cdd:cd00609 63 VVTNGAQEALSLLLRALLNPGDEvLVPDP-----TYPGYEAAARLAGAEVVPVPLDEEGgflldleLLEAAKTPKTKLLY 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 153 FETPANPTLKIIDMERVCK--DAHSQEGVLVIADNTFC--------SPMITNPVDFGVDVVVHSATKYINghtdvVAGL- 221
Cdd:cd00609 138 LNNPNNPTGAVLSEEELEElaELAKKHGILIISDEAYAelvydgepPPALALLDAYERVIVLRSFSKTFG-----LPGLr 212
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
1E5E_A 222 ----ICGKADLLQQIRMvgIKDITGSVISPHDAWLITRGLST----LNIRMKAESENAMKVAEYLKSHPAVEKVYYPG 291
Cdd:cd00609 213 igylIAPPEELLERLKK--LLPYTTSGPSTLSQAAAAAALDDgeehLEELRERYRRRRDALLEALKELGPLVVVKPSG 288
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
83-233 |
2.51e-04 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 43.00 E-value: 2.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 83 TSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFIN-----TAIPGEVKKHMKPNTKIVYFETPA 157
Cdd:pfam00266 70 TTEAINLVALSLGRSLKPGDEIVITEMEHHANLVPWQELAKRTGARVRVLPldedgLLDLDELEKLITPKTKLVAITHVS 149
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
1E5E_A 158 NPTLKIIDMERVCKDAHsQEGVLVIADntFCSPMITNPVD---FGVDVVVHSATKyINGHTDVvaGLICGKADLLQQIR 233
Cdd:pfam00266 150 NVTGTIQPVPEIGKLAH-QYGALVLVD--AAQAIGHRPIDvqkLGVDFLAFSGHK-LYGPTGI--GVLYGRRDLLEKMP 222
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
81-235 |
5.36e-04 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 41.65 E-value: 5.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 81 VATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHAltkfGIQVDFINTAI-------PGEVKKHMKPNTKIVYF 153
Cdd:COG0436 94 LVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLA----GGKPVPVPLDEengflpdPEALEAAITPRTKAIVL 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 154 ETPANPTLKIIDME------RVCKDaHsqeGVLVIADNT----------FCSPMiTNPVDFGVDVVVHSATKYINghtdv 217
Cdd:COG0436 170 NSPNNPTGAVYSREelealaELARE-H---DLLVISDEIyeelvydgaeHVSIL-SLPGLKDRTIVINSFSKSYA----- 239
|
170 180
....*....|....*....|..
1E5E_A 218 VAGL----ICGKADLLQQIRMV 235
Cdd:COG0436 240 MTGWrigyAVGPPELIAALLKL 261
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
77-187 |
1.49e-03 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 40.62 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1E5E_A 77 TEACVaTSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKF-GIQVDFINTAIP-GEVKKHMKPNTKIVYFE 154
Cdd:PLN00175 116 KEVTV-TSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIkTVTLRPPDFAVPeDELKAAFTSKTRAILIN 194
|
90 100 110
....*....|....*....|....*....|....*....
1E5E_A 155 TPANPTLKIIDMERV------CKdahsQEGVLVIADNTF 187
Cdd:PLN00175 195 TPHNPTGKMFTREELeliaslCK----ENDVLAFTDEVY 229
|
|
| |
